Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3082c

Experiment: 7H9 with para-aminosalicylic 0.086 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3081 and Rv3082c are separated by 125 nucleotidesRv3082c and Rv3083 are separated by 77 nucleotides Rv3081: Rv3081 - Conserved hypothetical protein, at 3,446,040 to 3,447,278 Rv3081 Rv3082c: Rv3082c - Virulence-regulating transcriptional regulator VirS (AraC/XylS family), at 3,447,404 to 3,448,426 Rv3082c Rv3083: Rv3083 - Probable monooxygenase (hydroxylase), at 3,448,504 to 3,449,991 Rv3083 Position (kb) 3447 3448 3449Strain fitness (log2 ratio) -2 -1 0 1 2at 3447.076 kb on + strand, within Rv3081at 3447.193 kb on + strandat 3447.277 kb on - strandat 3447.287 kb on + strandat 3447.426 kb on + strandat 3447.426 kb on + strandat 3447.529 kb on - strand, within Rv3082cat 3447.549 kb on + strand, within Rv3082cat 3447.549 kb on + strand, within Rv3082cat 3447.550 kb on - strand, within Rv3082cat 3447.551 kb on - strand, within Rv3082cat 3447.747 kb on + strand, within Rv3082cat 3447.869 kb on - strand, within Rv3082cat 3448.111 kb on - strand, within Rv3082cat 3448.384 kb on - strandat 3448.384 kb on - strandat 3448.753 kb on + strand, within Rv3083at 3448.753 kb on + strand, within Rv3083at 3448.753 kb on + strand, within Rv3083at 3448.906 kb on + strand, within Rv3083at 3448.907 kb on - strand, within Rv3083at 3448.927 kb on + strand, within Rv3083at 3448.931 kb on - strand, within Rv3083at 3448.937 kb on - strand, within Rv3083at 3449.149 kb on + strand, within Rv3083at 3449.149 kb on + strand, within Rv3083at 3449.266 kb on + strand, within Rv3083at 3449.321 kb on + strand, within Rv3083

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with para-aminosalicylic 0.086 ug/mL
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3,447,076 + Rv3081 0.84 +0.3
3,447,193 + +0.4
3,447,277 - -0.2
3,447,287 + +0.1
3,447,426 + -1.8
3,447,426 + -0.3
3,447,529 - Rv3082c 0.12 +0.9
3,447,549 + Rv3082c 0.14 -1.0
3,447,549 + Rv3082c 0.14 -0.0
3,447,550 - Rv3082c 0.14 +0.4
3,447,551 - Rv3082c 0.14 -1.6
3,447,747 + Rv3082c 0.34 +0.3
3,447,869 - Rv3082c 0.45 -0.1
3,448,111 - Rv3082c 0.69 +0.9
3,448,384 - -0.3
3,448,384 - +0.1
3,448,753 + Rv3083 0.17 -0.3
3,448,753 + Rv3083 0.17 -0.3
3,448,753 + Rv3083 0.17 -0.7
3,448,906 + Rv3083 0.27 +1.0
3,448,907 - Rv3083 0.27 -0.5
3,448,927 + Rv3083 0.28 +1.0
3,448,931 - Rv3083 0.29 -1.6
3,448,937 - Rv3083 0.29 +0.2
3,449,149 + Rv3083 0.43 -0.2
3,449,149 + Rv3083 0.43 +2.0
3,449,266 + Rv3083 0.51 -0.4
3,449,321 + Rv3083 0.55 +0.6

Or see this region's nucleotide sequence