Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2781c

Experiment: 7H9 with para-aminosalicylic 0.086 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2780 and Rv2781c are separated by 14 nucleotidesRv2781c and Rv2782c are separated by 60 nucleotides Rv2780: Rv2780 - Secreted L-alanine dehydrogenase Ald (40 kDa antigen) (TB43), at 3,086,820 to 3,087,935 Rv2780 Rv2781c: Rv2781c - Possible alanine rich oxidoreductase, at 3,087,950 to 3,088,984 Rv2781c Rv2782c: Rv2782c - Probable zinc protease PepR, at 3,089,045 to 3,090,361 Rv2782c Position (kb) 3087 3088 3089Strain fitness (log2 ratio) -1 0 1at 3087.029 kb on - strand, within Rv2780at 3087.168 kb on + strand, within Rv2780at 3087.200 kb on - strand, within Rv2780at 3087.258 kb on + strand, within Rv2780at 3087.258 kb on + strand, within Rv2780at 3087.620 kb on - strand, within Rv2780at 3087.667 kb on - strand, within Rv2780at 3087.751 kb on - strand, within Rv2780at 3088.173 kb on + strand, within Rv2781cat 3088.174 kb on - strand, within Rv2781cat 3088.521 kb on + strand, within Rv2781cat 3088.675 kb on - strand, within Rv2781cat 3088.701 kb on + strand, within Rv2781cat 3088.702 kb on - strand, within Rv2781cat 3088.704 kb on + strand, within Rv2781cat 3088.705 kb on - strand, within Rv2781cat 3088.735 kb on - strand, within Rv2781cat 3088.857 kb on + strand, within Rv2781cat 3089.217 kb on + strand, within Rv2782cat 3089.410 kb on - strand, within Rv2782c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with para-aminosalicylic 0.086 ug/mL
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3,087,029 - Rv2780 0.19 -0.3
3,087,168 + Rv2780 0.31 +0.1
3,087,200 - Rv2780 0.34 -0.2
3,087,258 + Rv2780 0.39 -0.5
3,087,258 + Rv2780 0.39 +1.6
3,087,620 - Rv2780 0.72 -1.2
3,087,667 - Rv2780 0.76 +0.4
3,087,751 - Rv2780 0.83 +0.4
3,088,173 + Rv2781c 0.22 +0.4
3,088,174 - Rv2781c 0.22 +0.1
3,088,521 + Rv2781c 0.55 -0.2
3,088,675 - Rv2781c 0.70 +0.3
3,088,701 + Rv2781c 0.73 +0.6
3,088,702 - Rv2781c 0.73 +0.9
3,088,704 + Rv2781c 0.73 +1.4
3,088,705 - Rv2781c 0.73 +0.3
3,088,735 - Rv2781c 0.76 +0.2
3,088,857 + Rv2781c 0.88 +1.2
3,089,217 + Rv2782c 0.13 -0.8
3,089,410 - Rv2782c 0.28 -0.2

Or see this region's nucleotide sequence