Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2268c

Experiment: 7H9 with para-aminosalicylic 0.086 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2267c and Rv2268c overlap by 4 nucleotidesRv2268c and Rv2269c are separated by 12 nucleotidesRv2269c and Rv2270 are separated by 76 nucleotides Rv2267c: Rv2267c - Conserved hypothetical protein, at 2,541,644 to 2,542,810 Rv2267c Rv2268c: Rv2268c - Probable cytochrome P450 128 Cyp128, at 2,542,807 to 2,544,276 Rv2268c Rv2269c: Rv2269c - Hypothetical protein, at 2,544,289 to 2,544,621 Rv2269c Rv2270: Rv2270 - Probable lipoprotein LppN, at 2,544,698 to 2,545,225 Rv2270 Position (kb) 2542 2543 2544 2545Strain fitness (log2 ratio) -1 0 1 2at 2541.822 kb on + strand, within Rv2267cat 2541.973 kb on - strand, within Rv2267cat 2542.028 kb on + strand, within Rv2267cat 2542.046 kb on - strand, within Rv2267cat 2542.069 kb on - strand, within Rv2267cat 2542.119 kb on - strand, within Rv2267cat 2542.147 kb on + strand, within Rv2267cat 2542.235 kb on + strand, within Rv2267cat 2542.336 kb on + strand, within Rv2267cat 2542.337 kb on - strand, within Rv2267cat 2542.337 kb on - strand, within Rv2267cat 2542.900 kb on + strandat 2543.172 kb on + strand, within Rv2268cat 2543.246 kb on + strand, within Rv2268cat 2543.833 kb on - strand, within Rv2268cat 2543.873 kb on + strand, within Rv2268cat 2543.895 kb on - strand, within Rv2268cat 2544.300 kb on + strandat 2544.371 kb on - strand, within Rv2269cat 2544.371 kb on - strand, within Rv2269cat 2544.491 kb on + strand, within Rv2269cat 2544.491 kb on + strand, within Rv2269cat 2544.545 kb on + strand, within Rv2269cat 2544.678 kb on - strandat 2544.725 kb on + strandat 2544.726 kb on - strandat 2544.726 kb on - strandat 2544.992 kb on + strand, within Rv2270at 2545.113 kb on - strand, within Rv2270at 2545.136 kb on - strand, within Rv2270

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with para-aminosalicylic 0.086 ug/mL
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2,541,822 + Rv2267c 0.15 +0.1
2,541,973 - Rv2267c 0.28 -0.2
2,542,028 + Rv2267c 0.33 -1.1
2,542,046 - Rv2267c 0.34 -0.1
2,542,069 - Rv2267c 0.36 +2.0
2,542,119 - Rv2267c 0.41 -0.5
2,542,147 + Rv2267c 0.43 -0.6
2,542,235 + Rv2267c 0.51 -0.6
2,542,336 + Rv2267c 0.59 +0.7
2,542,337 - Rv2267c 0.59 -1.2
2,542,337 - Rv2267c 0.59 -0.9
2,542,900 + -0.5
2,543,172 + Rv2268c 0.25 -0.0
2,543,246 + Rv2268c 0.30 -0.9
2,543,833 - Rv2268c 0.70 -0.3
2,543,873 + Rv2268c 0.73 -1.3
2,543,895 - Rv2268c 0.74 -0.1
2,544,300 + -0.2
2,544,371 - Rv2269c 0.25 +0.4
2,544,371 - Rv2269c 0.25 -0.8
2,544,491 + Rv2269c 0.61 +0.3
2,544,491 + Rv2269c 0.61 -0.5
2,544,545 + Rv2269c 0.77 -0.6
2,544,678 - -0.1
2,544,725 + -0.9
2,544,726 - +0.5
2,544,726 - -0.4
2,544,992 + Rv2270 0.56 -0.3
2,545,113 - Rv2270 0.79 +0.3
2,545,136 - Rv2270 0.83 -0.4

Or see this region's nucleotide sequence