Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2183c

Experiment: 7H9 with para-aminosalicylic 0.086 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2181 and Rv2182c are separated by 0 nucleotidesRv2182c and Rv2183c are separated by 85 nucleotidesRv2183c and Rv2184c overlap by 4 nucleotides Rv2181: Rv2181 - Alpha(1->2)mannosyltransferase, at 2,443,302 to 2,444,585 Rv2181 Rv2182c: Rv2182c - 1-acylglycerol-3-phosphate O-acyltransferase, at 2,444,586 to 2,445,329 Rv2182c Rv2183c: Rv2183c - Conserved protein, at 2,445,415 to 2,445,810 Rv2183c Rv2184c: Rv2184c - Conserved hypothetical protein, at 2,445,807 to 2,446,946 Rv2184c Position (kb) 2445 2446Strain fitness (log2 ratio) -1 0 1at 2444.472 kb on + strandat 2444.472 kb on + strandat 2444.473 kb on - strandat 2444.587 kb on + strandat 2445.373 kb on + strandat 2445.637 kb on + strand, within Rv2183cat 2445.849 kb on + strandat 2446.017 kb on + strand, within Rv2184cat 2446.055 kb on + strand, within Rv2184cat 2446.055 kb on + strand, within Rv2184cat 2446.055 kb on + strand, within Rv2184cat 2446.055 kb on + strand, within Rv2184cat 2446.279 kb on + strand, within Rv2184cat 2446.556 kb on - strand, within Rv2184c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with para-aminosalicylic 0.086 ug/mL
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2,444,472 + +0.2
2,444,472 + -0.0
2,444,473 - +0.3
2,444,587 + +1.2
2,445,373 + -0.5
2,445,637 + Rv2183c 0.56 +0.3
2,445,849 + +0.0
2,446,017 + Rv2184c 0.18 +0.2
2,446,055 + Rv2184c 0.22 +0.3
2,446,055 + Rv2184c 0.22 +0.7
2,446,055 + Rv2184c 0.22 +1.0
2,446,055 + Rv2184c 0.22 +0.3
2,446,279 + Rv2184c 0.41 +1.0
2,446,556 - Rv2184c 0.66 -0.2

Or see this region's nucleotide sequence