Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1912c

Experiment: 7H9 with para-aminosalicylic 0.086 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1910c and Rv1911c are separated by 82 nucleotidesRv1911c and Rv1912c are separated by 99 nucleotidesRv1912c and Rv1913 are separated by 99 nucleotidesRv1913 and Rv1914c overlap by 23 nucleotides Rv1910c: Rv1910c - Probable exported protein, at 2,156,706 to 2,157,299 Rv1910c Rv1911c: Rv1911c - Probable lipoprotein LppC, at 2,157,382 to 2,157,987 Rv1911c Rv1912c: Rv1912c - Possible oxidoreductase FadB5, at 2,158,087 to 2,159,091 Rv1912c Rv1913: Rv1913 - Conserved hypothetical protein, at 2,159,191 to 2,159,943 Rv1913 Rv1914c: Rv1914c - Unknown protein, at 2,159,921 to 2,160,328 Rv1914c Position (kb) 2158 2159 2160Strain fitness (log2 ratio) -1 0 1at 2157.135 kb on + strand, within Rv1910cat 2157.162 kb on - strand, within Rv1910cat 2157.162 kb on - strand, within Rv1910cat 2157.555 kb on - strand, within Rv1911cat 2157.663 kb on - strand, within Rv1911cat 2157.663 kb on - strand, within Rv1911cat 2157.878 kb on + strand, within Rv1911cat 2157.878 kb on + strand, within Rv1911cat 2157.959 kb on - strandat 2158.010 kb on + strandat 2158.010 kb on + strandat 2158.011 kb on - strandat 2158.013 kb on + strandat 2158.436 kb on + strand, within Rv1912cat 2158.436 kb on + strand, within Rv1912cat 2158.437 kb on - strand, within Rv1912cat 2158.688 kb on + strand, within Rv1912cat 2159.091 kb on + strandat 2159.145 kb on + strandat 2159.179 kb on - strandat 2159.288 kb on + strand, within Rv1913at 2159.289 kb on - strand, within Rv1913at 2159.472 kb on - strand, within Rv1913at 2159.578 kb on + strand, within Rv1913at 2159.793 kb on - strand, within Rv1913at 2159.922 kb on + strandat 2159.923 kb on - strandat 2159.923 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with para-aminosalicylic 0.086 ug/mL
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2,157,135 + Rv1910c 0.72 -0.4
2,157,162 - Rv1910c 0.77 -0.2
2,157,162 - Rv1910c 0.77 +0.0
2,157,555 - Rv1911c 0.29 +0.0
2,157,663 - Rv1911c 0.46 -1.3
2,157,663 - Rv1911c 0.46 +0.6
2,157,878 + Rv1911c 0.82 -0.9
2,157,878 + Rv1911c 0.82 +0.4
2,157,959 - -0.2
2,158,010 + -0.1
2,158,010 + -0.8
2,158,011 - +1.0
2,158,013 + -0.3
2,158,436 + Rv1912c 0.35 +1.0
2,158,436 + Rv1912c 0.35 +0.1
2,158,437 - Rv1912c 0.35 +0.5
2,158,688 + Rv1912c 0.60 +0.0
2,159,091 + -0.4
2,159,145 + +0.1
2,159,179 - -0.4
2,159,288 + Rv1913 0.13 +0.3
2,159,289 - Rv1913 0.13 +0.4
2,159,472 - Rv1913 0.37 -1.3
2,159,578 + Rv1913 0.51 -0.0
2,159,793 - Rv1913 0.80 -0.1
2,159,922 + -0.1
2,159,923 - -0.1
2,159,923 - -0.5

Or see this region's nucleotide sequence