Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1761c

Experiment: 7H9 with para-aminosalicylic 0.086 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1760 and Rv1761c are separated by 9 nucleotidesRv1761c and Rv1762c overlap by 1 nucleotides Rv1760: Rv1760 - Possible triacylglycerol synthase (diacylglycerol acyltransferase), at 1,993,153 to 1,994,661 Rv1760 Rv1761c: Rv1761c - Possible exported protein, at 1,994,671 to 1,995,054 Rv1761c Rv1762c: Rv1762c - Unknown protein, at 1,995,054 to 1,995,842 Rv1762c Position (kb) 1994 1995 1996Strain fitness (log2 ratio) -1 0 1at 1993.976 kb on - strand, within Rv1760at 1993.977 kb on + strand, within Rv1760at 1993.977 kb on + strand, within Rv1760at 1994.082 kb on - strand, within Rv1760at 1994.259 kb on + strand, within Rv1760at 1994.373 kb on + strand, within Rv1760at 1994.373 kb on + strand, within Rv1760at 1994.383 kb on + strand, within Rv1760at 1994.428 kb on + strand, within Rv1760at 1994.428 kb on + strand, within Rv1760at 1994.429 kb on - strand, within Rv1760at 1994.667 kb on - strandat 1994.667 kb on - strandat 1994.667 kb on - strandat 1994.744 kb on + strand, within Rv1761cat 1994.876 kb on + strand, within Rv1761cat 1994.876 kb on + strand, within Rv1761cat 1994.940 kb on + strand, within Rv1761cat 1994.940 kb on + strand, within Rv1761cat 1994.941 kb on - strand, within Rv1761cat 1995.133 kb on + strand, within Rv1762cat 1995.133 kb on + strand, within Rv1762cat 1995.134 kb on - strand, within Rv1762cat 1995.163 kb on + strand, within Rv1762cat 1995.163 kb on + strand, within Rv1762cat 1995.164 kb on - strand, within Rv1762cat 1995.259 kb on + strand, within Rv1762cat 1995.259 kb on + strand, within Rv1762cat 1995.259 kb on + strand, within Rv1762cat 1995.259 kb on + strand, within Rv1762cat 1995.259 kb on + strand, within Rv1762cat 1995.260 kb on - strand, within Rv1762cat 1995.260 kb on - strand, within Rv1762cat 1995.346 kb on - strand, within Rv1762cat 1995.695 kb on - strand, within Rv1762cat 1995.695 kb on - strand, within Rv1762cat 1995.816 kb on + strandat 1996.030 kb on + strandat 1996.049 kb on + strandat 1996.049 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with para-aminosalicylic 0.086 ug/mL
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1,993,976 - Rv1760 0.55 +0.0
1,993,977 + Rv1760 0.55 -0.7
1,993,977 + Rv1760 0.55 -0.7
1,994,082 - Rv1760 0.62 -0.9
1,994,259 + Rv1760 0.73 -0.6
1,994,373 + Rv1760 0.81 +0.1
1,994,373 + Rv1760 0.81 +0.1
1,994,383 + Rv1760 0.82 -0.4
1,994,428 + Rv1760 0.84 -0.5
1,994,428 + Rv1760 0.84 -0.2
1,994,429 - Rv1760 0.85 -0.7
1,994,667 - +0.4
1,994,667 - +0.8
1,994,667 - +0.0
1,994,744 + Rv1761c 0.19 +0.4
1,994,876 + Rv1761c 0.53 +1.0
1,994,876 + Rv1761c 0.53 +0.0
1,994,940 + Rv1761c 0.70 +0.0
1,994,940 + Rv1761c 0.70 +1.0
1,994,941 - Rv1761c 0.70 +0.0
1,995,133 + Rv1762c 0.10 +0.0
1,995,133 + Rv1762c 0.10 -1.0
1,995,134 - Rv1762c 0.10 -0.2
1,995,163 + Rv1762c 0.14 -0.2
1,995,163 + Rv1762c 0.14 +0.5
1,995,164 - Rv1762c 0.14 +0.2
1,995,259 + Rv1762c 0.26 +1.6
1,995,259 + Rv1762c 0.26 +0.2
1,995,259 + Rv1762c 0.26 -1.5
1,995,259 + Rv1762c 0.26 +0.2
1,995,259 + Rv1762c 0.26 -0.5
1,995,260 - Rv1762c 0.26 +0.3
1,995,260 - Rv1762c 0.26 -0.6
1,995,346 - Rv1762c 0.37 +0.4
1,995,695 - Rv1762c 0.81 -0.4
1,995,695 - Rv1762c 0.81 +0.5
1,995,816 + -0.2
1,996,030 + +0.4
1,996,049 + +0.4
1,996,049 + +0.4

Or see this region's nucleotide sequence