Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1239c

Experiment: 7H9 with para-aminosalicylic 0.086 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1238 and Rv1239c are separated by 76 nucleotidesRv1239c and Rv1240 are separated by 170 nucleotides Rv1238: Rv1238 - Probable sugar-transport ATP-binding protein ABC transporter SugC, at 1,380,684 to 1,381,865 Rv1238 Rv1239c: Rv1239c - Possible magnesium and cobalt transport transmembrane protein CorA, at 1,381,942 to 1,383,042 Rv1239c Rv1240: Rv1240 - Probable malate dehydrogenase Mdh, at 1,383,213 to 1,384,202 Rv1240 Position (kb) 1381 1382 1383 1384Strain fitness (log2 ratio) -1 0 1at 1380.953 kb on + strand, within Rv1238at 1381.252 kb on - strand, within Rv1238at 1381.300 kb on + strand, within Rv1238at 1381.569 kb on + strand, within Rv1238at 1381.644 kb on + strand, within Rv1238at 1381.885 kb on - strandat 1381.885 kb on - strandat 1381.885 kb on - strandat 1381.885 kb on - strandat 1381.943 kb on + strandat 1381.990 kb on - strandat 1382.066 kb on + strand, within Rv1239cat 1382.196 kb on - strand, within Rv1239cat 1382.364 kb on - strand, within Rv1239cat 1382.405 kb on - strand, within Rv1239cat 1382.472 kb on - strand, within Rv1239cat 1382.472 kb on - strand, within Rv1239cat 1382.499 kb on - strand, within Rv1239cat 1382.670 kb on - strand, within Rv1239cat 1382.888 kb on + strand, within Rv1239cat 1382.894 kb on + strand, within Rv1239cat 1382.895 kb on - strand, within Rv1239cat 1383.113 kb on - strandat 1383.125 kb on + strandat 1383.171 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with para-aminosalicylic 0.086 ug/mL
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1,380,953 + Rv1238 0.23 -0.0
1,381,252 - Rv1238 0.48 +0.2
1,381,300 + Rv1238 0.52 +0.8
1,381,569 + Rv1238 0.75 +0.8
1,381,644 + Rv1238 0.81 +0.9
1,381,885 - +0.3
1,381,885 - -0.2
1,381,885 - +0.1
1,381,885 - +0.2
1,381,943 + -1.1
1,381,990 - +0.5
1,382,066 + Rv1239c 0.11 +0.2
1,382,196 - Rv1239c 0.23 -0.2
1,382,364 - Rv1239c 0.38 +1.3
1,382,405 - Rv1239c 0.42 +0.2
1,382,472 - Rv1239c 0.48 +1.3
1,382,472 - Rv1239c 0.48 -0.0
1,382,499 - Rv1239c 0.51 +0.1
1,382,670 - Rv1239c 0.66 +0.2
1,382,888 + Rv1239c 0.86 +0.6
1,382,894 + Rv1239c 0.86 -0.2
1,382,895 - Rv1239c 0.87 +0.6
1,383,113 - -0.4
1,383,125 + +1.2
1,383,171 + -0.1

Or see this region's nucleotide sequence