Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0383c

Experiment: 7H9 with para-aminosalicylic 0.086 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0381c and Rv0382c are separated by 17 nucleotidesRv0382c and Rv0383c are separated by 80 nucleotidesRv0383c and Rv0384c are separated by 140 nucleotides Rv0381c: Rv0381c - Hypothetical protein, at 456,915 to 457,823 Rv0381c Rv0382c: Rv0382c - Probable orotate phosphoribosyltransferase PyrE (OPRT) (oprtase), at 457,841 to 458,380 Rv0382c Rv0383c: Rv0383c - Possible conserved secreted protein, at 458,461 to 459,315 Rv0383c Rv0384c: Rv0384c - Probable endopeptidase ATP binding protein (chain B) ClpB (ClpB protein) (heat shock protein F84.1), at 459,456 to 462,002 Rv0384c Position (kb) 458 459 460Strain fitness (log2 ratio) -2 -1 0 1at 457.645 kb on + strand, within Rv0381cat 457.645 kb on + strand, within Rv0381cat 457.645 kb on + strand, within Rv0381cat 457.646 kb on - strand, within Rv0381cat 458.624 kb on - strand, within Rv0383c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with para-aminosalicylic 0.086 ug/mL
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457,645 + Rv0381c 0.80 -0.4
457,645 + Rv0381c 0.80 -1.9
457,645 + Rv0381c 0.80 -0.4
457,646 - Rv0381c 0.80 -0.8
458,624 - Rv0383c 0.19 +0.6

Or see this region's nucleotide sequence