Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0131c

Experiment: 7H9 with para-aminosalicylic 0.086 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0129c and Rv0130 are separated by 246 nucleotidesRv0130 and Rv0131c are separated by 12 nucleotidesRv0131c and Rv0132c are separated by 41 nucleotides Rv0129c: Rv0129c - Secreted antigen 85-C FbpC (85C) (antigen 85 complex C) (AG58C) (mycolyl transferase 85C) (fibronectin-binding protein C), at 156,578 to 157,600 Rv0129c Rv0130: Rv0130 - Probable 3-hydroxyl-thioester dehydratase, at 157,847 to 158,302 Rv0130 Rv0131c: Rv0131c - Probable acyl-CoA dehydrogenase FadE1, at 158,315 to 159,658 Rv0131c Rv0132c: Rv0132c - Putative F420-dependent glucose-6-phosphate dehydrogenase Fgd2, at 159,700 to 160,782 Rv0132c Position (kb) 158 159 160Strain fitness (log2 ratio) -1 0 1at 157.327 kb on - strand, within Rv0129cat 157.435 kb on - strand, within Rv0129cat 157.435 kb on - strand, within Rv0129cat 157.525 kb on + strandat 157.600 kb on + strandat 157.601 kb on - strandat 157.604 kb on + strandat 157.607 kb on + strandat 157.818 kb on - strandat 157.823 kb on + strandat 157.824 kb on - strandat 158.079 kb on - strand, within Rv0130at 158.291 kb on + strandat 158.638 kb on - strand, within Rv0131cat 158.761 kb on + strand, within Rv0131cat 158.840 kb on + strand, within Rv0131cat 159.045 kb on + strand, within Rv0131cat 159.046 kb on - strand, within Rv0131cat 159.592 kb on - strandat 160.264 kb on + strand, within Rv0132cat 160.264 kb on + strand, within Rv0132cat 160.265 kb on - strand, within Rv0132cat 160.265 kb on - strand, within Rv0132cat 160.265 kb on - strand, within Rv0132cat 160.302 kb on - strand, within Rv0132cat 160.302 kb on - strand, within Rv0132cat 160.427 kb on + strand, within Rv0132cat 160.433 kb on + strand, within Rv0132cat 160.433 kb on + strand, within Rv0132cat 160.433 kb on + strand, within Rv0132cat 160.434 kb on - strand, within Rv0132cat 160.434 kb on - strand, within Rv0132cat 160.434 kb on - strand, within Rv0132cat 160.434 kb on - strand, within Rv0132cat 160.436 kb on - strand, within Rv0132cat 160.546 kb on + strand, within Rv0132cat 160.546 kb on + strand, within Rv0132cat 160.547 kb on - strand, within Rv0132cat 160.547 kb on - strand, within Rv0132cat 160.568 kb on + strand, within Rv0132cat 160.569 kb on - strand, within Rv0132c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with para-aminosalicylic 0.086 ug/mL
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157,327 - Rv0129c 0.73 -1.3
157,435 - Rv0129c 0.84 -0.3
157,435 - Rv0129c 0.84 -0.6
157,525 + -0.6
157,600 + +0.0
157,601 - +0.7
157,604 + -0.8
157,607 + -0.6
157,818 - +1.5
157,823 + -0.2
157,824 - +0.1
158,079 - Rv0130 0.51 -0.4
158,291 + +0.0
158,638 - Rv0131c 0.24 +0.8
158,761 + Rv0131c 0.33 +1.3
158,840 + Rv0131c 0.39 -1.1
159,045 + Rv0131c 0.54 -0.3
159,046 - Rv0131c 0.54 -0.3
159,592 - +0.1
160,264 + Rv0132c 0.52 -0.6
160,264 + Rv0132c 0.52 +0.0
160,265 - Rv0132c 0.52 +0.5
160,265 - Rv0132c 0.52 +0.2
160,265 - Rv0132c 0.52 -0.4
160,302 - Rv0132c 0.56 -0.2
160,302 - Rv0132c 0.56 -0.5
160,427 + Rv0132c 0.67 +1.0
160,433 + Rv0132c 0.68 -0.7
160,433 + Rv0132c 0.68 -0.2
160,433 + Rv0132c 0.68 -0.2
160,434 - Rv0132c 0.68 -0.6
160,434 - Rv0132c 0.68 -0.3
160,434 - Rv0132c 0.68 +0.4
160,434 - Rv0132c 0.68 -0.4
160,436 - Rv0132c 0.68 -0.5
160,546 + Rv0132c 0.78 -0.3
160,546 + Rv0132c 0.78 -0.2
160,547 - Rv0132c 0.78 -0.2
160,547 - Rv0132c 0.78 +0.3
160,568 + Rv0132c 0.80 -0.1
160,569 - Rv0132c 0.80 +1.0

Or see this region's nucleotide sequence