Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0081

Experiment: 7H9 with para-aminosalicylic 0.086 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0079 and Rv0080 overlap by 4 nucleotidesRv0080 and Rv0081 are separated by 94 nucleotidesRv0081 and Rv0082 are separated by 4 nucleotidesRv0082 and Rv0083 overlap by 4 nucleotides Rv0079: Rv0079 - Unknown protein, at 88,204 to 89,025 Rv0079 Rv0080: Rv0080 - Conserved hypothetical protein, at 89,022 to 89,480 Rv0080 Rv0081: Rv0081 - Probable transcriptional regulatory protein, at 89,575 to 89,919 Rv0081 Rv0082: Rv0082 - Probable oxidoreductase, at 89,924 to 90,403 Rv0082 Rv0083: Rv0083 - Probable oxidoreductase, at 90,400 to 92,322 Rv0083 Position (kb) 89 90Strain fitness (log2 ratio) -2 -1 0 1at 88.631 kb on + strand, within Rv0079at 88.681 kb on + strand, within Rv0079at 88.682 kb on - strand, within Rv0079at 88.732 kb on + strand, within Rv0079at 88.779 kb on - strand, within Rv0079at 88.779 kb on - strand, within Rv0079at 88.954 kb on + strandat 88.954 kb on + strandat 89.271 kb on + strand, within Rv0080at 89.271 kb on + strand, within Rv0080at 89.272 kb on - strand, within Rv0080at 89.370 kb on + strand, within Rv0080at 89.371 kb on - strand, within Rv0080at 89.471 kb on + strandat 89.472 kb on - strandat 89.593 kb on + strandat 89.594 kb on - strandat 89.747 kb on + strand, within Rv0081at 89.917 kb on + strandat 90.015 kb on + strand, within Rv0082at 90.101 kb on + strand, within Rv0082at 90.290 kb on + strand, within Rv0082at 90.322 kb on - strand, within Rv0082at 90.497 kb on + strandat 90.497 kb on + strandat 90.607 kb on + strand, within Rv0083at 90.607 kb on + strand, within Rv0083at 90.608 kb on - strand, within Rv0083at 90.608 kb on - strand, within Rv0083at 90.608 kb on - strand, within Rv0083at 90.619 kb on + strand, within Rv0083at 90.620 kb on - strand, within Rv0083at 90.811 kb on + strand, within Rv0083at 90.811 kb on + strand, within Rv0083

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with para-aminosalicylic 0.086 ug/mL
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88,631 + Rv0079 0.52 -0.1
88,681 + Rv0079 0.58 -0.4
88,682 - Rv0079 0.58 -0.1
88,732 + Rv0079 0.64 +1.4
88,779 - Rv0079 0.70 -0.6
88,779 - Rv0079 0.70 -1.1
88,954 + -0.2
88,954 + -0.1
89,271 + Rv0080 0.54 -0.3
89,271 + Rv0080 0.54 -0.6
89,272 - Rv0080 0.54 -0.1
89,370 + Rv0080 0.76 -0.7
89,371 - Rv0080 0.76 -0.5
89,471 + -0.1
89,472 - +0.0
89,593 + -1.5
89,594 - +0.2
89,747 + Rv0081 0.50 +0.7
89,917 + -0.3
90,015 + Rv0082 0.19 +1.1
90,101 + Rv0082 0.37 -0.5
90,290 + Rv0082 0.76 -0.7
90,322 - Rv0082 0.83 -0.2
90,497 + +0.1
90,497 + -0.2
90,607 + Rv0083 0.11 +0.3
90,607 + Rv0083 0.11 +0.2
90,608 - Rv0083 0.11 -0.3
90,608 - Rv0083 0.11 -1.8
90,608 - Rv0083 0.11 +0.0
90,619 + Rv0083 0.11 -0.2
90,620 - Rv0083 0.11 +0.5
90,811 + Rv0083 0.21 -0.6
90,811 + Rv0083 0.21 -0.1

Or see this region's nucleotide sequence