Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2615c

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2614c and Rv2614A are separated by 108 nucleotidesRv2614A and Rv2615c overlap by 4 nucleotidesRv2615c and Rv2616 are separated by 344 nucleotidesRv2616 and Rv2617c are separated by 16 nucleotides Rv2614c: Rv2614c - Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase), at 2,941,189 to 2,943,267 Rv2614c Rv2614A: Rv2614A - Conserved hypothetical protein, at 2,943,376 to 2,943,603 Rv2614A Rv2615c: Rv2615c - PE-PGRS family protein PE_PGRS45, at 2,943,600 to 2,944,985 Rv2615c Rv2616: Rv2616 - Conserved protein, at 2,945,330 to 2,945,830 Rv2616 Rv2617c: Rv2617c - Probable transmembrane protein, at 2,945,847 to 2,946,287 Rv2617c Position (kb) 2943 2944 2945Strain fitness (log2 ratio) -1 0 1at 2943.340 kb on + strandat 2943.341 kb on - strandat 2943.923 kb on + strand, within Rv2615cat 2943.979 kb on + strand, within Rv2615cat 2943.980 kb on - strand, within Rv2615cat 2943.980 kb on - strand, within Rv2615cat 2943.980 kb on - strand, within Rv2615cat 2945.411 kb on + strand, within Rv2616at 2945.603 kb on + strand, within Rv2616at 2945.603 kb on + strand, within Rv2616at 2945.603 kb on + strand, within Rv2616at 2945.604 kb on - strand, within Rv2616at 2945.604 kb on - strand, within Rv2616at 2945.813 kb on + strandat 2945.814 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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2,943,340 + +0.6
2,943,341 - +1.3
2,943,923 + Rv2615c 0.23 -1.1
2,943,979 + Rv2615c 0.27 +1.0
2,943,980 - Rv2615c 0.27 -0.5
2,943,980 - Rv2615c 0.27 -0.0
2,943,980 - Rv2615c 0.27 -0.2
2,945,411 + Rv2616 0.16 +0.5
2,945,603 + Rv2616 0.54 -0.8
2,945,603 + Rv2616 0.54 -0.6
2,945,603 + Rv2616 0.54 -1.5
2,945,604 - Rv2616 0.55 -0.5
2,945,604 - Rv2616 0.55 -0.1
2,945,813 + -0.4
2,945,814 - -0.7

Or see this region's nucleotide sequence