Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2370c

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2368c and Rv2369c overlap by 29 nucleotidesRv2369c and Rv2370c overlap by 4 nucleotidesRv2370c and Rv2371 are separated by 194 nucleotidesRv2371 and Rv2372c are separated by 98 nucleotides Rv2368c: Rv2368c - Probable PHOH-like protein PhoH1 (phosphate starvation-inducible protein PSIH), at 2,648,916 to 2,649,974 Rv2368c Rv2369c: Rv2369c - Hypothetical protein, at 2,649,946 to 2,650,248 Rv2369c Rv2370c: Rv2370c - Conserved hypothetical protein, at 2,650,245 to 2,651,558 Rv2370c Rv2371: Rv2371 - PE-PGRS family protein PE_PGRS40, at 2,651,753 to 2,651,938 Rv2371 Rv2372c: Rv2372c - Conserved hypothetical protein, at 2,652,037 to 2,652,825 Rv2372c Position (kb) 2650 2651 2652Strain fitness (log2 ratio) -2 -1 0 1at 2649.257 kb on + strand, within Rv2368cat 2649.269 kb on - strand, within Rv2368cat 2649.353 kb on - strand, within Rv2368cat 2649.353 kb on - strand, within Rv2368cat 2649.363 kb on + strand, within Rv2368cat 2649.363 kb on + strand, within Rv2368cat 2649.364 kb on - strand, within Rv2368cat 2649.368 kb on - strand, within Rv2368cat 2649.368 kb on - strand, within Rv2368cat 2649.368 kb on - strand, within Rv2368cat 2649.448 kb on - strand, within Rv2368cat 2649.502 kb on + strand, within Rv2368cat 2649.502 kb on + strand, within Rv2368cat 2649.503 kb on - strand, within Rv2368cat 2649.694 kb on - strand, within Rv2368cat 2649.871 kb on - strandat 2650.047 kb on + strand, within Rv2369cat 2650.307 kb on + strandat 2650.307 kb on + strandat 2650.446 kb on + strand, within Rv2370cat 2650.447 kb on - strand, within Rv2370cat 2650.470 kb on + strand, within Rv2370cat 2650.470 kb on + strand, within Rv2370cat 2650.471 kb on - strand, within Rv2370cat 2650.471 kb on - strand, within Rv2370cat 2650.473 kb on + strand, within Rv2370cat 2650.513 kb on + strand, within Rv2370cat 2650.514 kb on - strand, within Rv2370cat 2650.514 kb on - strand, within Rv2370cat 2650.521 kb on + strand, within Rv2370cat 2650.824 kb on + strand, within Rv2370cat 2650.940 kb on - strand, within Rv2370cat 2650.940 kb on - strand, within Rv2370cat 2651.084 kb on - strand, within Rv2370cat 2651.084 kb on - strand, within Rv2370cat 2651.271 kb on + strand, within Rv2370cat 2651.272 kb on - strand, within Rv2370cat 2651.304 kb on + strand, within Rv2370cat 2651.413 kb on - strand, within Rv2370cat 2651.569 kb on + strandat 2651.570 kb on - strandat 2651.578 kb on - strandat 2651.645 kb on + strandat 2651.734 kb on + strandat 2651.734 kb on + strandat 2651.735 kb on - strandat 2652.060 kb on - strandat 2652.060 kb on - strandat 2652.350 kb on - strand, within Rv2372c

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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2,649,257 + Rv2368c 0.32 -0.2
2,649,269 - Rv2368c 0.33 -0.5
2,649,353 - Rv2368c 0.41 -1.5
2,649,353 - Rv2368c 0.41 +0.0
2,649,363 + Rv2368c 0.42 +0.2
2,649,363 + Rv2368c 0.42 -0.4
2,649,364 - Rv2368c 0.42 -0.5
2,649,368 - Rv2368c 0.43 -0.2
2,649,368 - Rv2368c 0.43 -0.5
2,649,368 - Rv2368c 0.43 +1.1
2,649,448 - Rv2368c 0.50 -0.9
2,649,502 + Rv2368c 0.55 -0.2
2,649,502 + Rv2368c 0.55 -0.2
2,649,503 - Rv2368c 0.55 -0.4
2,649,694 - Rv2368c 0.73 -0.5
2,649,871 - -0.2
2,650,047 + Rv2369c 0.33 +0.2
2,650,307 + -0.3
2,650,307 + -0.4
2,650,446 + Rv2370c 0.15 -0.6
2,650,447 - Rv2370c 0.15 -0.8
2,650,470 + Rv2370c 0.17 -0.4
2,650,470 + Rv2370c 0.17 -1.9
2,650,471 - Rv2370c 0.17 -0.3
2,650,471 - Rv2370c 0.17 -0.3
2,650,473 + Rv2370c 0.17 -0.6
2,650,513 + Rv2370c 0.20 -0.8
2,650,514 - Rv2370c 0.20 +0.7
2,650,514 - Rv2370c 0.20 +0.3
2,650,521 + Rv2370c 0.21 -1.0
2,650,824 + Rv2370c 0.44 +0.7
2,650,940 - Rv2370c 0.53 -0.7
2,650,940 - Rv2370c 0.53 -1.2
2,651,084 - Rv2370c 0.64 +0.7
2,651,084 - Rv2370c 0.64 -0.3
2,651,271 + Rv2370c 0.78 -0.1
2,651,272 - Rv2370c 0.78 -0.3
2,651,304 + Rv2370c 0.81 -0.2
2,651,413 - Rv2370c 0.89 -0.8
2,651,569 + -0.3
2,651,570 - -0.2
2,651,578 - +1.3
2,651,645 + +1.1
2,651,734 + -0.0
2,651,734 + -0.0
2,651,735 - -0.5
2,652,060 - -0.4
2,652,060 - -0.2
2,652,350 - Rv2372c 0.40 -0.9

Or see this region's nucleotide sequence