Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1469

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1468c and Rv1469 are separated by 241 nucleotidesRv1469 and Rv1470 are separated by 43 nucleotidesRv1470 and Rv1471 are separated by 15 nucleotidesRv1471 and Rv1472 are separated by 21 nucleotides Rv1468c: Rv1468c - PE-PGRS family protein PE_PGRS29, at 1,655,609 to 1,656,721 Rv1468c Rv1469: Rv1469 - Probable cation transporter P-type ATPase D CtpD, at 1,656,963 to 1,658,936 Rv1469 Rv1470: Rv1470 - Probable thioredoxin TrxA, at 1,658,980 to 1,659,354 Rv1470 Rv1471: Rv1471 - Probable thioredoxin TrxB1, at 1,659,370 to 1,659,741 Rv1471 Rv1472: Rv1472 - Possible enoyl-CoA hydratase EchA12 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase), at 1,659,763 to 1,660,620 Rv1472 Position (kb) 1656 1657 1658 1659Strain fitness (log2 ratio) -1 0 1 2at 1656.462 kb on + strand, within Rv1468cat 1656.462 kb on + strand, within Rv1468cat 1656.463 kb on - strand, within Rv1468cat 1656.538 kb on - strand, within Rv1468cat 1656.538 kb on - strand, within Rv1468cat 1656.647 kb on - strandat 1656.746 kb on - strandat 1656.746 kb on - strandat 1656.758 kb on - strandat 1657.164 kb on + strand, within Rv1469at 1657.164 kb on + strand, within Rv1469at 1657.176 kb on + strand, within Rv1469at 1657.177 kb on - strand, within Rv1469at 1657.177 kb on - strand, within Rv1469at 1657.633 kb on + strand, within Rv1469at 1657.634 kb on - strand, within Rv1469at 1657.634 kb on - strand, within Rv1469at 1657.800 kb on - strand, within Rv1469at 1657.800 kb on - strand, within Rv1469at 1657.983 kb on - strand, within Rv1469at 1658.269 kb on - strand, within Rv1469at 1658.666 kb on - strand, within Rv1469at 1658.934 kb on + strandat 1658.935 kb on - strandat 1659.008 kb on - strandat 1659.097 kb on + strand, within Rv1470at 1659.097 kb on + strand, within Rv1470at 1659.098 kb on - strand, within Rv1470at 1659.296 kb on - strand, within Rv1470at 1659.296 kb on - strand, within Rv1470at 1659.296 kb on - strand, within Rv1470at 1659.296 kb on - strand, within Rv1470at 1659.296 kb on - strand, within Rv1470at 1659.296 kb on - strand, within Rv1470

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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1,656,462 + Rv1468c 0.77 +1.1
1,656,462 + Rv1468c 0.77 -0.5
1,656,463 - Rv1468c 0.77 -1.7
1,656,538 - Rv1468c 0.83 +0.3
1,656,538 - Rv1468c 0.83 +0.1
1,656,647 - -0.1
1,656,746 - -0.1
1,656,746 - -0.2
1,656,758 - -1.2
1,657,164 + Rv1469 0.10 -0.1
1,657,164 + Rv1469 0.10 -0.1
1,657,176 + Rv1469 0.11 -0.3
1,657,177 - Rv1469 0.11 +0.9
1,657,177 - Rv1469 0.11 +1.9
1,657,633 + Rv1469 0.34 -0.4
1,657,634 - Rv1469 0.34 +0.2
1,657,634 - Rv1469 0.34 -0.1
1,657,800 - Rv1469 0.42 +1.1
1,657,800 - Rv1469 0.42 +1.1
1,657,983 - Rv1469 0.52 +0.1
1,658,269 - Rv1469 0.66 +0.7
1,658,666 - Rv1469 0.86 +0.2
1,658,934 + +1.2
1,658,935 - -0.0
1,659,008 - +0.6
1,659,097 + Rv1470 0.31 -0.3
1,659,097 + Rv1470 0.31 -0.2
1,659,098 - Rv1470 0.31 -0.3
1,659,296 - Rv1470 0.84 +1.7
1,659,296 - Rv1470 0.84 +1.3
1,659,296 - Rv1470 0.84 -0.2
1,659,296 - Rv1470 0.84 -0.5
1,659,296 - Rv1470 0.84 +0.3
1,659,296 - Rv1470 0.84 -0.4

Or see this region's nucleotide sequence