Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0447c

Experiment: no stress control

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv0445c and Rv0446c are separated by 48 nucleotidesRv0446c and Rv0447c are separated by 8 nucleotidesRv0447c and Rv0448c overlap by 4 nucleotidesRv0448c and Rv0449c are separated by 59 nucleotides Rv0445c: Rv0445c - Alternative RNA polymerase sigma factor SigK, at 533,833 to 534,396 Rv0445c Rv0446c: Rv0446c - Possible conserved transmembrane protein, at 534,445 to 535,215 Rv0446c Rv0447c: Rv0447c - Probable cyclopropane-fatty-acyl-phospholipid synthase UfaA1 (cyclopropane fatty acid synthase) (CFA synthase), at 535,224 to 536,507 Rv0447c Rv0448c: Rv0448c - Conserved hypothetical protein, at 536,504 to 537,169 Rv0448c Rv0449c: Rv0449c - Conserved hypothetical protein, at 537,229 to 538,548 Rv0449c Position (kb) 535 536 537Strain fitness (log2 ratio) -2 -1 0 1at 534.248 kb on + strand, within Rv0445cat 534.285 kb on - strand, within Rv0445cat 534.285 kb on - strand, within Rv0445cat 534.309 kb on - strand, within Rv0445cat 534.483 kb on - strandat 534.530 kb on + strand, within Rv0446cat 534.668 kb on + strand, within Rv0446cat 534.669 kb on - strand, within Rv0446cat 534.742 kb on + strand, within Rv0446cat 534.898 kb on + strand, within Rv0446cat 534.992 kb on + strand, within Rv0446cat 534.992 kb on + strand, within Rv0446cat 534.992 kb on + strand, within Rv0446cat 535.036 kb on + strand, within Rv0446cat 535.037 kb on - strand, within Rv0446cat 535.039 kb on + strand, within Rv0446cat 535.118 kb on - strand, within Rv0446cat 535.136 kb on + strand, within Rv0446cat 535.136 kb on + strand, within Rv0446cat 535.136 kb on + strand, within Rv0446cat 535.258 kb on + strandat 535.259 kb on - strandat 535.307 kb on - strandat 535.344 kb on + strandat 535.373 kb on + strand, within Rv0447cat 535.374 kb on - strand, within Rv0447cat 535.409 kb on - strand, within Rv0447cat 535.513 kb on + strand, within Rv0447cat 535.514 kb on - strand, within Rv0447cat 535.514 kb on - strand, within Rv0447cat 535.618 kb on - strand, within Rv0447cat 535.681 kb on - strand, within Rv0447cat 535.681 kb on - strand, within Rv0447cat 535.690 kb on + strand, within Rv0447cat 535.691 kb on - strand, within Rv0447cat 535.999 kb on + strand, within Rv0447cat 536.050 kb on + strand, within Rv0447cat 536.061 kb on + strand, within Rv0447cat 536.061 kb on + strand, within Rv0447cat 536.062 kb on - strand, within Rv0447cat 536.062 kb on - strand, within Rv0447cat 536.062 kb on - strand, within Rv0447cat 536.062 kb on - strand, within Rv0447cat 536.062 kb on - strand, within Rv0447cat 536.062 kb on - strand, within Rv0447cat 536.062 kb on - strand, within Rv0447cat 536.064 kb on - strand, within Rv0447cat 536.064 kb on - strand, within Rv0447cat 536.227 kb on + strand, within Rv0447cat 536.228 kb on - strand, within Rv0447cat 536.228 kb on - strand, within Rv0447cat 536.739 kb on - strand, within Rv0448cat 536.745 kb on + strand, within Rv0448cat 536.746 kb on - strand, within Rv0448cat 536.746 kb on - strand, within Rv0448cat 536.746 kb on - strand, within Rv0448cat 536.779 kb on - strand, within Rv0448cat 536.779 kb on - strand, within Rv0448cat 536.820 kb on - strand, within Rv0448cat 536.826 kb on + strand, within Rv0448cat 536.826 kb on + strand, within Rv0448cat 536.928 kb on + strand, within Rv0448cat 537.029 kb on - strand, within Rv0448cat 537.132 kb on + strandat 537.133 kb on - strandat 537.142 kb on - strandat 537.142 kb on - strandat 537.142 kb on - strandat 537.205 kb on - strand

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
remove
534,248 + Rv0445c 0.74 -0.4
534,285 - Rv0445c 0.80 +0.1
534,285 - Rv0445c 0.80 -1.9
534,309 - Rv0445c 0.84 -0.6
534,483 - -0.2
534,530 + Rv0446c 0.11 -0.0
534,668 + Rv0446c 0.29 -0.5
534,669 - Rv0446c 0.29 -0.4
534,742 + Rv0446c 0.39 -0.0
534,898 + Rv0446c 0.59 -0.4
534,992 + Rv0446c 0.71 +1.1
534,992 + Rv0446c 0.71 -0.1
534,992 + Rv0446c 0.71 +1.1
535,036 + Rv0446c 0.77 -1.1
535,037 - Rv0446c 0.77 +1.4
535,039 + Rv0446c 0.77 +0.5
535,118 - Rv0446c 0.87 +0.1
535,136 + Rv0446c 0.90 +0.0
535,136 + Rv0446c 0.90 -0.8
535,136 + Rv0446c 0.90 -0.1
535,258 + -0.4
535,259 - -0.1
535,307 - -2.5
535,344 + -1.2
535,373 + Rv0447c 0.12 +0.4
535,374 - Rv0447c 0.12 -0.0
535,409 - Rv0447c 0.14 -0.5
535,513 + Rv0447c 0.23 -0.1
535,514 - Rv0447c 0.23 -0.8
535,514 - Rv0447c 0.23 +0.6
535,618 - Rv0447c 0.31 -0.4
535,681 - Rv0447c 0.36 +0.4
535,681 - Rv0447c 0.36 -2.3
535,690 + Rv0447c 0.36 -0.5
535,691 - Rv0447c 0.36 -2.4
535,999 + Rv0447c 0.60 +0.5
536,050 + Rv0447c 0.64 -0.9
536,061 + Rv0447c 0.65 -0.7
536,061 + Rv0447c 0.65 -0.3
536,062 - Rv0447c 0.65 -0.4
536,062 - Rv0447c 0.65 -0.7
536,062 - Rv0447c 0.65 -0.6
536,062 - Rv0447c 0.65 -0.3
536,062 - Rv0447c 0.65 +0.6
536,062 - Rv0447c 0.65 +0.6
536,062 - Rv0447c 0.65 -0.5
536,064 - Rv0447c 0.65 -0.8
536,064 - Rv0447c 0.65 -0.1
536,227 + Rv0447c 0.78 -0.6
536,228 - Rv0447c 0.78 -0.9
536,228 - Rv0447c 0.78 -0.7
536,739 - Rv0448c 0.35 -0.7
536,745 + Rv0448c 0.36 +0.2
536,746 - Rv0448c 0.36 -0.9
536,746 - Rv0448c 0.36 -0.0
536,746 - Rv0448c 0.36 -1.0
536,779 - Rv0448c 0.41 -0.2
536,779 - Rv0448c 0.41 -2.4
536,820 - Rv0448c 0.47 +0.1
536,826 + Rv0448c 0.48 -0.0
536,826 + Rv0448c 0.48 +0.0
536,928 + Rv0448c 0.64 +0.6
537,029 - Rv0448c 0.79 -2.3
537,132 + -0.3
537,133 - +0.8
537,142 - -0.9
537,142 - +1.7
537,142 - -2.3
537,205 - -0.6

Or see this region's nucleotide sequence