Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3501c

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3499c and Rv3500c are separated by 19 nucleotidesRv3500c and Rv3501c are separated by 34 nucleotidesRv3501c and Rv3502c are separated by 225 nucleotides Rv3499c: Rv3499c - Mce-family protein Mce4A, at 3,917,998 to 3,919,200 Rv3499c Rv3500c: Rv3500c - Conserved integral membrane protein YrbE4B. Possible ABC transporter., at 3,919,220 to 3,920,062 Rv3500c Rv3501c: Rv3501c - Conserved integral membrane protein YrbE4A. Possible ABC transporter., at 3,920,097 to 3,920,861 Rv3501c Rv3502c: Rv3502c - Probable short-chain type dehydrogenase/reductase. Possible 17-beta-hydroxysteroid dehydrogenase., at 3,921,087 to 3,922,040 Rv3502c Position (kb) 3920 3921Strain fitness (log2 ratio) -2 -1 0 1at 3919.101 kb on + strandat 3919.104 kb on - strandat 3919.255 kb on - strandat 3919.363 kb on - strand, within Rv3500cat 3919.369 kb on - strand, within Rv3500cat 3919.369 kb on - strand, within Rv3500cat 3919.371 kb on + strand, within Rv3500cat 3919.372 kb on - strand, within Rv3500cat 3919.376 kb on - strand, within Rv3500cat 3919.376 kb on - strand, within Rv3500cat 3919.376 kb on - strand, within Rv3500cat 3919.402 kb on + strand, within Rv3500cat 3919.403 kb on - strand, within Rv3500cat 3919.418 kb on - strand, within Rv3500cat 3919.461 kb on + strand, within Rv3500cat 3919.462 kb on - strand, within Rv3500cat 3919.470 kb on + strand, within Rv3500cat 3919.471 kb on - strand, within Rv3500cat 3919.471 kb on - strand, within Rv3500cat 3919.548 kb on + strand, within Rv3500cat 3919.549 kb on - strand, within Rv3500cat 3919.549 kb on - strand, within Rv3500cat 3919.600 kb on - strand, within Rv3500cat 3919.800 kb on + strand, within Rv3500cat 3919.956 kb on + strand, within Rv3500cat 3919.956 kb on + strand, within Rv3500cat 3919.956 kb on + strand, within Rv3500cat 3919.957 kb on - strand, within Rv3500cat 3919.957 kb on - strand, within Rv3500cat 3919.957 kb on - strand, within Rv3500cat 3919.957 kb on - strand, within Rv3500cat 3919.974 kb on + strand, within Rv3500cat 3920.055 kb on + strandat 3920.056 kb on - strandat 3920.056 kb on - strandat 3920.121 kb on + strandat 3920.121 kb on + strandat 3920.121 kb on + strandat 3920.122 kb on - strandat 3920.122 kb on - strandat 3920.136 kb on + strandat 3920.136 kb on + strandat 3920.136 kb on + strandat 3920.137 kb on - strandat 3920.137 kb on - strandat 3920.289 kb on + strand, within Rv3501cat 3920.290 kb on - strand, within Rv3501cat 3920.290 kb on - strand, within Rv3501cat 3920.330 kb on + strand, within Rv3501cat 3920.331 kb on - strand, within Rv3501cat 3920.718 kb on + strand, within Rv3501cat 3921.030 kb on - strandat 3921.064 kb on - strandat 3921.075 kb on + strandat 3921.076 kb on - strandat 3921.145 kb on + strandat 3921.146 kb on - strandat 3921.146 kb on - strandat 3921.315 kb on + strand, within Rv3502cat 3921.315 kb on + strand, within Rv3502cat 3921.315 kb on + strand, within Rv3502cat 3921.315 kb on + strand, within Rv3502cat 3921.316 kb on - strand, within Rv3502cat 3921.316 kb on - strand, within Rv3502cat 3921.436 kb on + strand, within Rv3502cat 3921.437 kb on - strand, within Rv3502cat 3921.605 kb on - strand, within Rv3502cat 3921.795 kb on - strand, within Rv3502c

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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3,919,101 + -0.5
3,919,104 - -1.2
3,919,255 - +1.3
3,919,363 - Rv3500c 0.17 -0.5
3,919,369 - Rv3500c 0.18 -1.0
3,919,369 - Rv3500c 0.18 +0.0
3,919,371 + Rv3500c 0.18 -0.5
3,919,372 - Rv3500c 0.18 -1.9
3,919,376 - Rv3500c 0.19 -0.5
3,919,376 - Rv3500c 0.19 -1.3
3,919,376 - Rv3500c 0.19 -1.4
3,919,402 + Rv3500c 0.22 -0.5
3,919,403 - Rv3500c 0.22 -0.0
3,919,418 - Rv3500c 0.23 +0.5
3,919,461 + Rv3500c 0.29 -1.7
3,919,462 - Rv3500c 0.29 -2.4
3,919,470 + Rv3500c 0.30 -1.7
3,919,471 - Rv3500c 0.30 -1.4
3,919,471 - Rv3500c 0.30 -1.7
3,919,548 + Rv3500c 0.39 +1.1
3,919,549 - Rv3500c 0.39 -1.5
3,919,549 - Rv3500c 0.39 -0.0
3,919,600 - Rv3500c 0.45 -0.9
3,919,800 + Rv3500c 0.69 +0.7
3,919,956 + Rv3500c 0.87 -1.8
3,919,956 + Rv3500c 0.87 -1.0
3,919,956 + Rv3500c 0.87 -0.3
3,919,957 - Rv3500c 0.87 -0.9
3,919,957 - Rv3500c 0.87 +1.3
3,919,957 - Rv3500c 0.87 -0.5
3,919,957 - Rv3500c 0.87 -0.1
3,919,974 + Rv3500c 0.89 -0.4
3,920,055 + +1.0
3,920,056 - -0.8
3,920,056 - +0.5
3,920,121 + -0.2
3,920,121 + -0.9
3,920,121 + -1.5
3,920,122 - -0.0
3,920,122 - -0.9
3,920,136 + -0.7
3,920,136 + -0.5
3,920,136 + -1.6
3,920,137 - -1.3
3,920,137 - -0.3
3,920,289 + Rv3501c 0.25 -0.9
3,920,290 - Rv3501c 0.25 +1.1
3,920,290 - Rv3501c 0.25 -0.6
3,920,330 + Rv3501c 0.30 -0.3
3,920,331 - Rv3501c 0.31 +1.5
3,920,718 + Rv3501c 0.81 -1.4
3,921,030 - +0.2
3,921,064 - -0.4
3,921,075 + -0.3
3,921,076 - -0.4
3,921,145 + -0.7
3,921,146 - -0.8
3,921,146 - +0.4
3,921,315 + Rv3502c 0.24 -0.2
3,921,315 + Rv3502c 0.24 -1.6
3,921,315 + Rv3502c 0.24 +1.0
3,921,315 + Rv3502c 0.24 -0.2
3,921,316 - Rv3502c 0.24 +0.7
3,921,316 - Rv3502c 0.24 -0.0
3,921,436 + Rv3502c 0.37 +0.1
3,921,437 - Rv3502c 0.37 +0.4
3,921,605 - Rv3502c 0.54 -1.0
3,921,795 - Rv3502c 0.74 +0.3

Or see this region's nucleotide sequence