Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3419c

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3417c and Rv3418c are separated by 94 nucleotidesRv3418c and Rv3419c are separated by 266 nucleotidesRv3419c and Rv3420c overlap by 4 nucleotidesRv3420c and Rv3421c overlap by 4 nucleotides Rv3417c: Rv3417c - 60 kDa chaperonin 1 GroEL1 (protein CPN60-1) (GroEL protein 1), at 3,835,272 to 3,836,891 Rv3417c Rv3418c: Rv3418c - 10 kDa chaperonin GroES (protein CPN10) (protein GroES) (BCG-a heat shock protein) (10 kDa antigen), at 3,836,986 to 3,837,288 Rv3418c Rv3419c: Rv3419c - Probable O-sialoglycoprotein endopeptidase Gcp (glycoprotease), at 3,837,555 to 3,838,589 Rv3419c Rv3420c: Rv3420c - Ribosomal-protein-alanine acetyltransferase RimI (acetylating enzyme for N-terminal of ribosomal protein S18), at 3,838,586 to 3,839,062 Rv3420c Rv3421c: Rv3421c - Conserved hypothetical protein, at 3,839,059 to 3,839,694 Rv3421c Position (kb) 3837 3838 3839Strain fitness (log2 ratio) -1 0 1 2at 3836.873 kb on - strandat 3837.955 kb on + strand, within Rv3419cat 3838.167 kb on - strand, within Rv3419cat 3838.167 kb on - strand, within Rv3419cat 3838.220 kb on - strand, within Rv3419cat 3838.621 kb on - strandat 3838.800 kb on + strand, within Rv3420cat 3838.911 kb on + strand, within Rv3420cat 3838.912 kb on - strand, within Rv3420cat 3838.912 kb on - strand, within Rv3420cat 3839.102 kb on + strandat 3839.103 kb on - strandat 3839.103 kb on - strandat 3839.400 kb on - strand, within Rv3421c

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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3,836,873 - +1.0
3,837,955 + Rv3419c 0.39 +0.6
3,838,167 - Rv3419c 0.59 +1.3
3,838,167 - Rv3419c 0.59 -0.3
3,838,220 - Rv3419c 0.64 +2.3
3,838,621 - -0.3
3,838,800 + Rv3420c 0.45 -1.5
3,838,911 + Rv3420c 0.68 +0.8
3,838,912 - Rv3420c 0.68 -0.6
3,838,912 - Rv3420c 0.68 -0.4
3,839,102 + +1.0
3,839,103 - -0.1
3,839,103 - +0.1
3,839,400 - Rv3421c 0.54 -0.0

Or see this region's nucleotide sequence