Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1079

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1077 and Rv1078 are separated by 201 nucleotidesRv1078 and Rv1079 are separated by 31 nucleotidesRv1079 and Rv1080c are separated by 70 nucleotidesRv1080c and Rv1081c are separated by 185 nucleotides Rv1077: Rv1077 - Probable cystathionine beta-synthase Cbs (serine sulfhydrase) (beta-thionase) (hemoprotein H-450), at 1,201,717 to 1,203,111 Rv1077 Rv1078: Rv1078 - Probable proline-rich antigen homolog Pra, at 1,203,313 to 1,204,035 Rv1078 Rv1079: Rv1079 - Cystathionine gamma-synthase MetB (CGS) (O-succinylhomoserine [thiol]-lyase), at 1,204,067 to 1,205,233 Rv1079 Rv1080c: Rv1080c - Probable transcription elongation factor GreA (transcript cleavage factor GreA), at 1,205,304 to 1,205,798 Rv1080c Rv1081c: Rv1081c - Probable conserved membrane protein, at 1,205,984 to 1,206,418 Rv1081c Position (kb) 1204 1205 1206Strain fitness (log2 ratio) -1 0 1 2at 1203.067 kb on + strandat 1203.255 kb on + strandat 1203.256 kb on - strandat 1204.175 kb on + strandat 1204.175 kb on + strandat 1204.176 kb on - strandat 1204.232 kb on + strand, within Rv1079at 1204.359 kb on + strand, within Rv1079at 1204.360 kb on - strand, within Rv1079at 1204.419 kb on + strand, within Rv1079at 1204.419 kb on + strand, within Rv1079at 1204.419 kb on + strand, within Rv1079at 1204.419 kb on + strand, within Rv1079at 1204.451 kb on + strand, within Rv1079at 1204.499 kb on - strand, within Rv1079at 1204.691 kb on + strand, within Rv1079at 1204.812 kb on - strand, within Rv1079at 1205.231 kb on + strandat 1205.232 kb on - strandat 1205.232 kb on - strandat 1205.232 kb on - strandat 1205.232 kb on - strandat 1205.302 kb on - strandat 1205.305 kb on + strandat 1205.306 kb on - strandat 1205.306 kb on - strandat 1205.306 kb on - strandat 1205.831 kb on + strandat 1205.927 kb on - strandat 1205.938 kb on - strandat 1205.938 kb on - strandat 1205.974 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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1,203,067 + +1.1
1,203,255 + -0.9
1,203,256 - +0.0
1,204,175 + +0.2
1,204,175 + +0.5
1,204,176 - +1.9
1,204,232 + Rv1079 0.14 +0.4
1,204,359 + Rv1079 0.25 -0.1
1,204,360 - Rv1079 0.25 +1.5
1,204,419 + Rv1079 0.30 +0.6
1,204,419 + Rv1079 0.30 +0.9
1,204,419 + Rv1079 0.30 +0.1
1,204,419 + Rv1079 0.30 +1.3
1,204,451 + Rv1079 0.33 -0.4
1,204,499 - Rv1079 0.37 +0.3
1,204,691 + Rv1079 0.53 +2.1
1,204,812 - Rv1079 0.64 +0.1
1,205,231 + -0.7
1,205,232 - +0.2
1,205,232 - -0.0
1,205,232 - -0.3
1,205,232 - +0.9
1,205,302 - +0.8
1,205,305 + +0.9
1,205,306 - +0.0
1,205,306 - -0.1
1,205,306 - +0.4
1,205,831 + -0.9
1,205,927 - +0.1
1,205,938 - +0.1
1,205,938 - -0.3
1,205,974 - -0.3

Or see this region's nucleotide sequence