Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0215c

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0214 and Rv0215c are separated by 105 nucleotidesRv0215c and Rv0216 are separated by 56 nucleotides Rv0214: Rv0214 - Probable fatty-acid-CoA ligase FadD4 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase), at 256,064 to 257,677 Rv0214 Rv0215c: Rv0215c - Probable acyl-CoA dehydrogenase FadE3, at 257,783 to 258,856 Rv0215c Rv0216: Rv0216 - Double hotdog hydratase, at 258,913 to 259,926 Rv0216 Position (kb) 257 258 259Strain fitness (log2 ratio) -1 0 1 2at 257.069 kb on + strand, within Rv0214at 257.220 kb on - strand, within Rv0214at 257.247 kb on - strand, within Rv0214at 257.559 kb on + strandat 257.643 kb on - strandat 257.720 kb on + strandat 257.721 kb on - strandat 257.753 kb on - strandat 257.803 kb on - strandat 257.926 kb on - strand, within Rv0215cat 257.991 kb on + strand, within Rv0215cat 257.992 kb on - strand, within Rv0215cat 258.531 kb on + strand, within Rv0215cat 258.532 kb on - strand, within Rv0215cat 258.532 kb on - strand, within Rv0215cat 258.532 kb on - strand, within Rv0215cat 258.651 kb on + strand, within Rv0215cat 258.681 kb on + strand, within Rv0215cat 258.747 kb on + strand, within Rv0215cat 258.751 kb on + strandat 258.751 kb on + strandat 258.751 kb on + strandat 258.752 kb on - strandat 258.752 kb on - strandat 259.193 kb on - strand, within Rv0216

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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257,069 + Rv0214 0.62 -0.4
257,220 - Rv0214 0.72 -0.3
257,247 - Rv0214 0.73 -1.0
257,559 + -0.0
257,643 - -0.2
257,720 + +0.1
257,721 - +0.2
257,753 - -0.3
257,803 - +0.7
257,926 - Rv0215c 0.13 -0.1
257,991 + Rv0215c 0.19 -0.1
257,992 - Rv0215c 0.19 -0.5
258,531 + Rv0215c 0.70 +0.3
258,532 - Rv0215c 0.70 +1.6
258,532 - Rv0215c 0.70 +2.0
258,532 - Rv0215c 0.70 -0.5
258,651 + Rv0215c 0.81 +0.5
258,681 + Rv0215c 0.84 +0.0
258,747 + Rv0215c 0.90 +2.1
258,751 + -0.7
258,751 + +0.3
258,751 + +2.0
258,752 - -0.9
258,752 - -0.4
259,193 - Rv0216 0.28 -0.4

Or see this region's nucleotide sequence