Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3856c

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ofloxacin 0.8 ug/mL
4,327,493	-				+2.1
4,327,534	+				+0.2
4,327,534	+				-0.5
4,327,534	+				+0.3
4,327,534	+				+0.3
4,327,538	-				-1.1
4,327,732	+		Rv3855	0.28	-0.1
4,327,738	+		Rv3855	0.29	+0.1
4,327,739	-		Rv3855	0.29	+0.5
4,327,809	-		Rv3855	0.40	-0.4
4,328,152	-				+0.1
4,328,182	+				-2.1
4,328,197	+				+1.6
4,328,324	+				+1.9
4,328,325	-				+1.5
4,328,326	+				-1.2
4,328,326	+				-1.0
4,328,326	+				-0.3
4,328,326	+				-0.0
4,328,326	+				-0.7
4,328,327	-				-2.6
4,328,327	-				-3.2
4,328,327	-				-1.1
4,328,572	+		Rv3856c	0.17	-2.2
4,329,029	+		Rv3856c	0.62	-0.2
4,329,040	+		Rv3856c	0.63	+2.5
4,329,330	-				-0.8
4,329,371	+				-0.4
4,329,375	-				+0.0
4,329,495	+		Rv3857c	0.39	+0.5
4,329,495	+		Rv3857c	0.39	-1.2
4,329,565	+		Rv3857c	0.75	-1.4
4,329,565	+		Rv3857c	0.75	-0.8
4,329,566	-		Rv3857c	0.75	+0.8
4,329,630	-				-1.8
4,329,630	-				-0.3
4,329,640	+				-0.1
4,329,641	-				-0.4
4,329,641	-				-0.7
4,329,735	-				-3.1
4,329,879	+				+0.1
4,329,929	+				-0.5