Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3409c

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ofloxacin 0.8 ug/mL
3,826,054	+		Rv3406	0.82	-0.9
3,826,054	+		Rv3406	0.82	-0.7
3,826,102	-		Rv3406	0.87	-0.5
3,826,175	+				-0.6
3,826,242	-				-0.0
3,826,298	+		Rv3407	0.15	+0.1
3,826,298	+		Rv3407	0.15	+1.5
3,826,298	+		Rv3407	0.15	-0.1
3,826,299	-		Rv3407	0.16	-0.3
3,826,554	+				-1.2
3,826,554	+				-0.7
3,826,555	-				-0.6
3,826,555	-				-0.1
3,826,555	-				-0.7
3,826,555	-				+0.1
3,826,555	-				-2.1
3,826,557	-				-0.6
3,826,738	-		Rv3408	0.46	-0.3
3,826,742	-		Rv3408	0.47	-0.3
3,826,742	-		Rv3408	0.47	+0.8
3,826,817	-		Rv3408	0.65	+1.0
3,826,817	-		Rv3408	0.65	-0.5
3,826,817	-		Rv3408	0.65	-0.3
3,826,817	-		Rv3408	0.65	+0.5
3,826,962	+				-2.0
3,827,232	+		Rv3409c	0.14	-0.1
3,827,250	+		Rv3409c	0.15	+0.5
3,827,250	+		Rv3409c	0.15	-0.1
3,827,250	+		Rv3409c	0.15	-0.8
3,827,250	+		Rv3409c	0.15	-0.3
3,827,251	-		Rv3409c	0.15	-0.3
3,827,251	-		Rv3409c	0.15	-1.1
3,827,262	+		Rv3409c	0.16	-1.2
3,827,426	-		Rv3409c	0.25	-0.5
3,827,426	-		Rv3409c	0.25	+0.4
3,827,426	-		Rv3409c	0.25	-0.3
3,827,882	-		Rv3409c	0.51	-2.7
3,828,369	+		Rv3409c	0.79	-1.0
3,828,370	-		Rv3409c	0.79	+0.2
3,828,447	+		Rv3409c	0.84	+0.3
3,828,448	-		Rv3409c	0.84	+3.5
3,828,448	-		Rv3409c	0.84	-0.7
3,828,526	+		Rv3409c	0.88	-3.4
3,828,526	+		Rv3409c	0.88	-0.7
3,828,527	-		Rv3409c	0.88	+1.4
3,828,714	+				-1.2
3,828,736	+				-0.9
3,828,736	+				+0.4
3,828,737	-				+0.7
3,828,737	-				-1.9
3,828,748	+				+2.0
3,828,749	-				-0.4
3,828,749	-				-0.1
3,828,749	-				-0.1
3,828,749	-				+0.4
3,828,763	-				+0.3