Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3148

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ofloxacin 0.8 ug/mL
3,512,338	+		Rv3146	0.47	-0.1
3,512,338	+		Rv3146	0.47	+0.1
3,512,459	-		Rv3146	0.69	-0.1
3,512,540	+		Rv3146	0.83	+0.1
3,512,540	+		Rv3146	0.83	-2.4
3,512,544	+		Rv3146	0.84	-0.5
3,512,927	-		Rv3147	0.42	-0.7
3,513,007	-		Rv3147	0.53	-0.4
3,513,263	-		Rv3147	0.89	-1.7
3,513,484	+		Rv3148	0.11	-0.6
3,513,484	+		Rv3148	0.11	-1.9
3,513,897	-		Rv3148	0.42	-1.1
3,514,160	+		Rv3148	0.62	+0.8
3,514,273	-		Rv3148	0.71	-1.2
3,514,273	-		Rv3148	0.71	+0.8
3,514,494	+		Rv3148	0.87	-0.5
3,514,495	-		Rv3148	0.87	-1.2
3,514,539	-				-0.0
3,514,763	+		Rv3149	0.14	-0.8
3,514,868	-		Rv3149	0.28	+3.0
3,514,948	+		Rv3149	0.38	-0.3
3,514,948	+		Rv3149	0.38	+0.2
3,514,949	-		Rv3149	0.38	+0.1
3,514,957	+		Rv3149	0.40	+0.9
3,514,957	+		Rv3149	0.40	+0.6
3,514,958	-		Rv3149	0.40	-0.2
3,514,958	-		Rv3149	0.40	+0.1
3,515,297	+		Rv3149	0.84	+0.0
3,515,491	-				+0.8