Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3087

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv3086 and Rv3087 are separated by 37 nucleotidesRv3087 and Rv3088 overlap by 4 nucleotides Rv3086: Rv3086 - Probable zinc-type alcohol dehydrogenase AdhD (aldehyde reductase), at 3,451,781 to 3,452,887 Rv3086 Rv3087: Rv3087 - Possible triacylglycerol synthase (diacylglycerol acyltransferase), at 3,452,925 to 3,454,343 Rv3087 Rv3088: Rv3088 - Putative triacylglycerol synthase (diacylglycerol acyltransferase) Tgs4, at 3,454,340 to 3,455,764 Rv3088 Position (kb) 3452 3453 3454 3455Strain fitness (log2 ratio) -2 -1 0 1 2at 3451.933 kb on - strand, within Rv3086at 3452.066 kb on + strand, within Rv3086at 3452.351 kb on + strand, within Rv3086at 3452.351 kb on + strand, within Rv3086at 3452.407 kb on + strand, within Rv3086at 3452.408 kb on - strand, within Rv3086at 3452.408 kb on - strand, within Rv3086at 3452.408 kb on - strand, within Rv3086at 3452.408 kb on - strand, within Rv3086at 3452.411 kb on + strand, within Rv3086at 3452.412 kb on - strand, within Rv3086at 3452.412 kb on - strand, within Rv3086at 3452.810 kb on + strandat 3452.810 kb on + strandat 3452.961 kb on + strandat 3452.962 kb on - strandat 3452.983 kb on - strandat 3453.105 kb on + strand, within Rv3087at 3453.387 kb on + strand, within Rv3087at 3453.388 kb on - strand, within Rv3087at 3453.388 kb on - strand, within Rv3087at 3453.388 kb on - strand, within Rv3087at 3453.760 kb on - strand, within Rv3087at 3453.760 kb on - strand, within Rv3087at 3453.856 kb on - strand, within Rv3087at 3453.870 kb on + strand, within Rv3087at 3454.223 kb on - strandat 3454.479 kb on - strandat 3454.688 kb on + strand, within Rv3088at 3454.688 kb on + strand, within Rv3088at 3454.688 kb on + strand, within Rv3088at 3454.688 kb on + strand, within Rv3088at 3454.689 kb on - strand, within Rv3088

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ofloxacin 0.8 ug/mL
remove
3,451,933 - Rv3086 0.14 -1.1
3,452,066 + Rv3086 0.26 -0.2
3,452,351 + Rv3086 0.51 +0.9
3,452,351 + Rv3086 0.51 -2.0
3,452,407 + Rv3086 0.57 -0.5
3,452,408 - Rv3086 0.57 -0.5
3,452,408 - Rv3086 0.57 +1.0
3,452,408 - Rv3086 0.57 -0.1
3,452,408 - Rv3086 0.57 +0.1
3,452,411 + Rv3086 0.57 +0.8
3,452,412 - Rv3086 0.57 -1.3
3,452,412 - Rv3086 0.57 -0.4
3,452,810 + -1.5
3,452,810 + -1.9
3,452,961 + -1.6
3,452,962 - +0.8
3,452,983 - -0.4
3,453,105 + Rv3087 0.13 +0.3
3,453,387 + Rv3087 0.33 -0.3
3,453,388 - Rv3087 0.33 +0.6
3,453,388 - Rv3087 0.33 +1.8
3,453,388 - Rv3087 0.33 +0.3
3,453,760 - Rv3087 0.59 +1.9
3,453,760 - Rv3087 0.59 -0.6
3,453,856 - Rv3087 0.66 +0.3
3,453,870 + Rv3087 0.67 +0.8
3,454,223 - -0.7
3,454,479 - -0.6
3,454,688 + Rv3088 0.24 -0.0
3,454,688 + Rv3088 0.24 +0.7
3,454,688 + Rv3088 0.24 -0.3
3,454,688 + Rv3088 0.24 -0.1
3,454,689 - Rv3088 0.24 -0.2

Or see this region's nucleotide sequence