Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2650c

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2649 and Rv2650c are separated by 373 nucleotidesRv2650c and Rv2651c are separated by 7 nucleotidesRv2651c and Rv2652c are separated by 152 nucleotides Rv2649: Rv2649 - Probable transposase for insertion sequence element IS6110, at 2,972,435 to 2,973,421 Rv2649 Rv2650c: Rv2650c - Possible PhiRv2 prophage protein, at 2,973,795 to 2,975,234 Rv2650c Rv2651c: Rv2651c - Possible PhiRv2 prophage protease, at 2,975,242 to 2,975,775 Rv2651c Rv2652c: Rv2652c - Probable PhiRv2 prophage protein, at 2,975,928 to 2,976,554 Rv2652c Position (kb) 2973 2974 2975 2976Strain fitness (log2 ratio) -1 0 1at 2974.252 kb on + strand, within Rv2650cat 2975.228 kb on + strandat 2975.244 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ofloxacin 0.8 ug/mL
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2,974,252 + Rv2650c 0.32 -0.7
2,975,228 + -0.1
2,975,244 - +0.3

Or see this region's nucleotide sequence