Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2630

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2629 and Rv2630 are separated by 1 nucleotidesRv2630 and Rv2631 are separated by 139 nucleotides Rv2629: Rv2629 - Conserved protein, at 2,955,767 to 2,956,891 Rv2629 Rv2630: Rv2630 - Hypothetical protein, at 2,956,893 to 2,957,432 Rv2630 Rv2631: Rv2631 - Conserved hypothetical protein, at 2,957,572 to 2,958,870 Rv2631 Position (kb) 2956 2957 2958Strain fitness (log2 ratio) -2 -1 0 1 2 3 4at 2956.014 kb on + strand, within Rv2629at 2956.079 kb on + strand, within Rv2629at 2956.080 kb on - strand, within Rv2629at 2956.096 kb on - strand, within Rv2629at 2956.096 kb on - strand, within Rv2629at 2956.125 kb on + strand, within Rv2629at 2956.125 kb on + strand, within Rv2629at 2956.126 kb on - strand, within Rv2629at 2956.166 kb on + strand, within Rv2629at 2956.514 kb on + strand, within Rv2629at 2956.687 kb on + strand, within Rv2629at 2956.828 kb on - strandat 2956.853 kb on + strandat 2956.853 kb on + strandat 2956.882 kb on + strandat 2956.883 kb on - strandat 2957.203 kb on + strand, within Rv2630at 2957.332 kb on + strand, within Rv2630at 2957.333 kb on - strand, within Rv2630at 2957.621 kb on - strandat 2957.727 kb on + strand, within Rv2631at 2957.727 kb on + strand, within Rv2631at 2957.741 kb on + strand, within Rv2631at 2957.742 kb on - strand, within Rv2631at 2957.742 kb on - strand, within Rv2631at 2958.088 kb on + strand, within Rv2631at 2958.089 kb on - strand, within Rv2631at 2958.320 kb on - strand, within Rv2631

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ofloxacin 0.8 ug/mL
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2,956,014 + Rv2629 0.22 -1.6
2,956,079 + Rv2629 0.28 +0.8
2,956,080 - Rv2629 0.28 -0.5
2,956,096 - Rv2629 0.29 -1.0
2,956,096 - Rv2629 0.29 +1.0
2,956,125 + Rv2629 0.32 +0.2
2,956,125 + Rv2629 0.32 +4.4
2,956,126 - Rv2629 0.32 -0.6
2,956,166 + Rv2629 0.35 +2.1
2,956,514 + Rv2629 0.66 -0.0
2,956,687 + Rv2629 0.82 +0.7
2,956,828 - +2.3
2,956,853 + -0.1
2,956,853 + -0.1
2,956,882 + -0.6
2,956,883 - -0.2
2,957,203 + Rv2630 0.57 +0.7
2,957,332 + Rv2630 0.81 -1.8
2,957,333 - Rv2630 0.81 -1.1
2,957,621 - +1.9
2,957,727 + Rv2631 0.12 -0.8
2,957,727 + Rv2631 0.12 -0.1
2,957,741 + Rv2631 0.13 +0.9
2,957,742 - Rv2631 0.13 -0.2
2,957,742 - Rv2631 0.13 -0.1
2,958,088 + Rv2631 0.40 -0.4
2,958,089 - Rv2631 0.40 -1.4
2,958,320 - Rv2631 0.58 -0.3

Or see this region's nucleotide sequence