Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2473

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ofloxacin 0.8 ug/mL
2,774,726	-		Rv2471	0.71	-1.6
2,774,993	+		Rv2471	0.87	-0.6
2,774,993	+		Rv2471	0.87	-1.3
2,774,993	+		Rv2471	0.87	-0.9
2,774,993	+		Rv2471	0.87	-0.2
2,774,997	+		Rv2471	0.87	-0.8
2,775,203	-				-0.3
2,775,203	-				-0.9
2,775,219	-				+1.8
2,775,219	-				+0.7
2,775,233	+				-0.0
2,775,233	+				-3.0
2,775,235	+				+0.2
2,775,235	+				-0.7
2,775,235	+				-2.0
2,775,236	-				+0.1
2,775,243	+				+0.2
2,775,271	+				-0.4
2,775,271	+				+0.3
2,775,272	-				-1.0
2,775,549	+				+0.3
2,775,549	+				-0.2
2,775,563	+				-2.1
2,775,697	-		Rv2473	0.18	-1.1
2,775,697	-		Rv2473	0.18	-1.4
2,775,715	+		Rv2473	0.21	-0.8
2,775,831	-		Rv2473	0.37	+0.6
2,775,851	+		Rv2473	0.39	-0.7
2,775,852	-		Rv2473	0.40	-1.7
2,776,176	-		Rv2473	0.85	-0.6
2,776,195	+		Rv2473	0.87	+0.1
2,776,196	-		Rv2473	0.88	+0.1
2,776,196	-		Rv2473	0.88	+0.4
2,776,223	+				+0.3
2,776,224	-				+0.3
2,776,641	+		Rv2474c	0.50	-0.5
2,776,977	-				+0.2
2,777,000	+				+0.6
2,777,001	-				-0.7
2,777,211	-		Rv2475c	0.57	+0.1
2,777,274	+		Rv2475c	0.72	-1.8