Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2417c

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2416c and Rv2417c are separated by 139 nucleotidesRv2417c and Rv2418c are separated by 80 nucleotidesRv2418c and Rv2419c overlap by 11 nucleotides Rv2416c: Rv2416c - Enhanced intracellular survival protein Eis,GCN5-related N-acetyltransferase, at 2,714,124 to 2,715,332 Rv2416c Rv2417c: Rv2417c - Conserved protein, at 2,715,472 to 2,716,314 Rv2417c Rv2418c: Rv2418c - Unknown protein, at 2,716,395 to 2,717,138 Rv2418c Rv2419c: Rv2419c - Glucosyl-3-phosphoglycerate phosphatase GpgP, at 2,717,128 to 2,717,799 Rv2419c Position (kb) 2715 2716 2717Strain fitness (log2 ratio) -1 0 1at 2714.472 kb on - strand, within Rv2416cat 2714.666 kb on - strand, within Rv2416cat 2714.859 kb on + strand, within Rv2416cat 2715.314 kb on + strandat 2715.375 kb on + strandat 2715.376 kb on - strandat 2715.473 kb on + strandat 2715.473 kb on + strandat 2715.906 kb on + strand, within Rv2417cat 2716.228 kb on - strand, within Rv2417cat 2716.291 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ofloxacin 0.8 ug/mL
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2,714,472 - Rv2416c 0.29 -1.6
2,714,666 - Rv2416c 0.45 -0.3
2,714,859 + Rv2416c 0.61 +0.5
2,715,314 + -0.6
2,715,375 + -0.4
2,715,376 - -0.4
2,715,473 + +1.1
2,715,473 + +0.4
2,715,906 + Rv2417c 0.51 -1.2
2,716,228 - Rv2417c 0.90 -1.0
2,716,291 - +0.7

Or see this region's nucleotide sequence