Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2409c

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ofloxacin 0.8 ug/mL
2,705,529	-				+0.3
2,705,759	+				-1.5
2,705,759	+				+1.0
2,705,759	+				-2.3
2,705,760	-				-2.2
2,705,760	-				-0.8
2,705,760	-				-0.1
2,705,790	+				-0.5
2,705,790	+				-0.4
2,705,790	+				+0.2
2,705,790	+				-1.6
2,705,790	+				+0.3
2,705,791	-				-2.9
2,705,791	-				+0.0
2,705,970	-				-0.6
2,706,038	-				+1.0
2,706,042	+				-2.9
2,706,042	+				+0.1
2,706,042	+				+0.0
2,706,042	+				+1.0
2,706,042	+				-2.5
2,706,042	+				-0.4
2,706,043	-				-2.2
2,706,043	-				-0.3
2,706,043	-				+0.9
2,706,043	-				-0.2
2,706,162	+		Rv2408	0.20	-0.3
2,706,162	+		Rv2408	0.20	-1.0
2,706,251	-		Rv2408	0.33	-1.3
2,706,553	-				-0.3
2,706,582	+				-0.4
2,706,594	-				-1.8
2,706,609	+				+0.4
2,706,699	-				+0.2
2,706,738	+		Rv2409c	0.29	-0.8
2,706,750	+		Rv2409c	0.30	-1.4
2,706,876	+		Rv2409c	0.45	-2.0
2,706,877	-		Rv2409c	0.46	-0.8
2,707,177	-		Rv2409c	0.81	-0.1
2,707,177	-		Rv2409c	0.81	-0.2
2,707,269	+				-2.2
2,707,712	+		Rv2410c	0.39	+0.5
2,707,712	+		Rv2410c	0.39	-1.0
2,707,712	+		Rv2410c	0.39	-1.2
2,707,976	+		Rv2410c	0.66	+0.1
2,707,976	+		Rv2410c	0.66	+3.0
2,708,283	-				+0.1