Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2317

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ofloxacin 0.8 ug/mL
2,588,815	+				+0.0
2,588,829	-				-0.3
2,588,874	+				+0.5
2,588,874	+				+1.5
2,588,875	-				-0.2
2,588,941	+		Rv2316	0.12	+0.4
2,588,941	+		Rv2316	0.12	+0.2
2,588,942	-		Rv2316	0.12	+1.0
2,588,942	-		Rv2316	0.12	-0.7
2,589,091	+		Rv2316	0.29	+0.7
2,589,159	+		Rv2316	0.37	-0.0
2,589,160	-		Rv2316	0.37	+1.0
2,589,362	-		Rv2316	0.60	-0.6
2,589,676	-				+0.7
2,589,709	-				-3.5
2,590,025	-		Rv2317	0.40	-1.0
2,590,640	-				+1.3
2,590,836	+		Rv2318	0.24	-0.1
2,591,187	+		Rv2318	0.51	+1.0
2,591,391	+		Rv2318	0.66	-0.0
2,591,392	-		Rv2318	0.66	+0.5