Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2077c

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2075c and Rv2076c are separated by 157 nucleotidesRv2076c and Rv2077c are separated by 34 nucleotidesRv2077c and Rv2077A are separated by 0 nucleotidesRv2077A and Rv2078 are separated by 464 nucleotides Rv2075c: Rv2075c - Possible hypothetical exported or envelope protein, at 2,331,416 to 2,332,879 Rv2075c Rv2076c: Rv2076c - Conserved hypothetical protein, at 2,333,037 to 2,333,288 Rv2076c Rv2077c: Rv2077c - Possible conserved transmembrane protein, at 2,333,323 to 2,334,294 Rv2077c Rv2077A: Rv2077A - Conserved hypothetical protein, at 2,334,295 to 2,334,594 Rv2077A Rv2078: Rv2078 - Conserved hypothetical protein, at 2,335,059 to 2,335,373 Rv2078 Position (kb) 2333 2334 2335Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 2332.392 kb on + strand, within Rv2075cat 2332.392 kb on + strand, within Rv2075cat 2332.392 kb on + strand, within Rv2075cat 2332.393 kb on - strand, within Rv2075cat 2332.393 kb on - strand, within Rv2075cat 2332.598 kb on + strand, within Rv2075cat 2332.598 kb on + strand, within Rv2075cat 2332.598 kb on + strand, within Rv2075cat 2332.598 kb on + strand, within Rv2075cat 2332.599 kb on - strand, within Rv2075cat 2332.599 kb on - strand, within Rv2075cat 2332.602 kb on + strand, within Rv2075cat 2332.602 kb on + strand, within Rv2075cat 2332.602 kb on + strand, within Rv2075cat 2332.742 kb on + strandat 2332.745 kb on + strandat 2332.789 kb on - strandat 2332.901 kb on - strandat 2332.901 kb on - strandat 2332.959 kb on - strandat 2332.993 kb on + strandat 2333.018 kb on + strandat 2333.019 kb on - strandat 2333.030 kb on + strandat 2333.031 kb on - strandat 2333.201 kb on + strand, within Rv2076cat 2333.202 kb on - strand, within Rv2076cat 2333.202 kb on - strand, within Rv2076cat 2333.212 kb on + strand, within Rv2076cat 2333.212 kb on + strand, within Rv2076cat 2333.212 kb on + strand, within Rv2076cat 2333.213 kb on - strand, within Rv2076cat 2333.324 kb on + strandat 2333.374 kb on + strandat 2333.389 kb on + strandat 2333.389 kb on + strandat 2333.390 kb on - strandat 2333.493 kb on + strand, within Rv2077cat 2333.493 kb on + strand, within Rv2077cat 2333.493 kb on + strand, within Rv2077cat 2333.493 kb on + strand, within Rv2077cat 2333.493 kb on + strand, within Rv2077cat 2333.493 kb on + strand, within Rv2077cat 2333.494 kb on - strand, within Rv2077cat 2333.494 kb on - strand, within Rv2077cat 2333.562 kb on + strand, within Rv2077cat 2333.749 kb on + strand, within Rv2077cat 2333.749 kb on + strand, within Rv2077cat 2333.750 kb on - strand, within Rv2077cat 2333.872 kb on + strand, within Rv2077cat 2333.908 kb on + strand, within Rv2077cat 2333.909 kb on - strand, within Rv2077cat 2333.963 kb on - strand, within Rv2077cat 2334.005 kb on - strand, within Rv2077cat 2334.005 kb on - strand, within Rv2077cat 2334.011 kb on + strand, within Rv2077cat 2334.012 kb on - strand, within Rv2077cat 2334.012 kb on - strand, within Rv2077cat 2334.012 kb on - strand, within Rv2077cat 2334.012 kb on - strand, within Rv2077cat 2334.012 kb on - strand, within Rv2077cat 2334.015 kb on + strand, within Rv2077cat 2334.015 kb on + strand, within Rv2077cat 2334.015 kb on + strand, within Rv2077cat 2334.015 kb on + strand, within Rv2077cat 2334.015 kb on + strand, within Rv2077cat 2334.016 kb on - strand, within Rv2077cat 2334.016 kb on - strand, within Rv2077cat 2334.016 kb on - strand, within Rv2077cat 2334.016 kb on - strand, within Rv2077cat 2334.039 kb on + strand, within Rv2077cat 2334.247 kb on - strandat 2334.297 kb on - strandat 2334.297 kb on - strandat 2334.297 kb on - strandat 2334.297 kb on - strandat 2334.359 kb on + strand, within Rv2077Aat 2334.359 kb on + strand, within Rv2077Aat 2334.360 kb on - strand, within Rv2077Aat 2334.448 kb on - strand, within Rv2077Aat 2334.630 kb on - strandat 2334.727 kb on + strandat 2334.981 kb on - strandat 2334.981 kb on - strandat 2335.029 kb on - strandat 2335.035 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ofloxacin 0.8 ug/mL
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2,332,392 + Rv2075c 0.67 -2.7
2,332,392 + Rv2075c 0.67 -0.4
2,332,392 + Rv2075c 0.67 +0.2
2,332,393 - Rv2075c 0.67 -0.3
2,332,393 - Rv2075c 0.67 +0.6
2,332,598 + Rv2075c 0.81 -0.3
2,332,598 + Rv2075c 0.81 -0.5
2,332,598 + Rv2075c 0.81 -0.5
2,332,598 + Rv2075c 0.81 -0.5
2,332,599 - Rv2075c 0.81 -0.4
2,332,599 - Rv2075c 0.81 -0.5
2,332,602 + Rv2075c 0.81 -0.5
2,332,602 + Rv2075c 0.81 +1.8
2,332,602 + Rv2075c 0.81 -0.7
2,332,742 + -0.2
2,332,745 + -0.6
2,332,789 - -2.8
2,332,901 - -1.7
2,332,901 - -1.0
2,332,959 - -0.1
2,332,993 + +0.3
2,333,018 + +0.5
2,333,019 - +1.5
2,333,030 + +0.4
2,333,031 - +0.6
2,333,201 + Rv2076c 0.65 -2.1
2,333,202 - Rv2076c 0.65 +1.1
2,333,202 - Rv2076c 0.65 -0.1
2,333,212 + Rv2076c 0.69 -0.4
2,333,212 + Rv2076c 0.69 +0.2
2,333,212 + Rv2076c 0.69 -0.2
2,333,213 - Rv2076c 0.70 -0.2
2,333,324 + +0.2
2,333,374 + +0.7
2,333,389 + -0.3
2,333,389 + -1.8
2,333,390 - -0.9
2,333,493 + Rv2077c 0.17 +1.8
2,333,493 + Rv2077c 0.17 -0.5
2,333,493 + Rv2077c 0.17 -1.0
2,333,493 + Rv2077c 0.17 -0.7
2,333,493 + Rv2077c 0.17 -0.5
2,333,493 + Rv2077c 0.17 -0.7
2,333,494 - Rv2077c 0.18 +0.8
2,333,494 - Rv2077c 0.18 -1.2
2,333,562 + Rv2077c 0.25 -0.9
2,333,749 + Rv2077c 0.44 -0.9
2,333,749 + Rv2077c 0.44 -1.9
2,333,750 - Rv2077c 0.44 -1.8
2,333,872 + Rv2077c 0.56 +0.2
2,333,908 + Rv2077c 0.60 -1.3
2,333,909 - Rv2077c 0.60 +0.1
2,333,963 - Rv2077c 0.66 -0.2
2,334,005 - Rv2077c 0.70 -0.5
2,334,005 - Rv2077c 0.70 -0.3
2,334,011 + Rv2077c 0.71 -0.2
2,334,012 - Rv2077c 0.71 -0.7
2,334,012 - Rv2077c 0.71 -0.2
2,334,012 - Rv2077c 0.71 -0.4
2,334,012 - Rv2077c 0.71 -1.3
2,334,012 - Rv2077c 0.71 +0.4
2,334,015 + Rv2077c 0.71 -0.9
2,334,015 + Rv2077c 0.71 +0.9
2,334,015 + Rv2077c 0.71 +0.7
2,334,015 + Rv2077c 0.71 -0.7
2,334,015 + Rv2077c 0.71 -0.7
2,334,016 - Rv2077c 0.71 +0.7
2,334,016 - Rv2077c 0.71 +0.3
2,334,016 - Rv2077c 0.71 +0.1
2,334,016 - Rv2077c 0.71 +1.1
2,334,039 + Rv2077c 0.74 -0.7
2,334,247 - -0.4
2,334,297 - -0.9
2,334,297 - -0.5
2,334,297 - -1.2
2,334,297 - -0.3
2,334,359 + Rv2077A 0.21 -0.0
2,334,359 + Rv2077A 0.21 -0.3
2,334,360 - Rv2077A 0.22 +0.2
2,334,448 - Rv2077A 0.51 +1.0
2,334,630 - -0.3
2,334,727 + -1.5
2,334,981 - -2.6
2,334,981 - -0.2
2,335,029 - +1.1
2,335,035 - -1.3

Or see this region's nucleotide sequence