Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2032

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ofloxacin 0.8 ug/mL
2,278,584	-		Rv2031c	0.20	+0.2
2,278,593	+		Rv2031c	0.22	+3.1
2,278,594	-		Rv2031c	0.22	-0.8
2,278,728	+		Rv2031c	0.53	+0.6
2,278,728	+		Rv2031c	0.53	-0.0
2,278,775	-		Rv2031c	0.64	-0.3
2,279,107	+				-0.1
2,279,663	+		Rv2032	0.54	-0.7
2,279,827	+		Rv2032	0.70	-1.1
2,279,850	-		Rv2032	0.72	-0.3
2,280,148	-				-0.4
2,280,241	+				-0.6
2,280,242	-				-0.4
2,280,328	-		Rv2033c	0.10	+0.6
2,280,328	-		Rv2033c	0.10	+0.1
2,280,493	+		Rv2033c	0.30	+1.8
2,280,493	+		Rv2033c	0.30	-0.2
2,280,748	+		Rv2033c	0.60	+0.3
2,280,877	-		Rv2033c	0.76	+1.3
2,280,880	+		Rv2033c	0.76	+0.9
2,281,090	+				-0.7
2,281,090	+				+1.5
2,281,090	+				-0.3
2,281,091	-				-0.4