Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1875

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ofloxacin 0.8 ug/mL
2,123,558	+		Rv1873	0.88	+0.9
2,123,559	-		Rv1873	0.88	+1.1
2,123,595	+				+0.7
2,123,609	+				-1.1
2,123,609	+				-0.3
2,123,609	+				+0.5
2,123,609	+				-1.4
2,123,610	-				-0.2
2,123,610	-				+0.1
2,123,653	+				-0.7
2,123,653	+				-1.1
2,123,653	+				-1.1
2,123,654	-				-0.4
2,123,797	+		Rv1874	0.16	+0.1
2,123,798	-		Rv1874	0.17	-0.2
2,123,834	+		Rv1874	0.22	-0.0
2,123,834	+		Rv1874	0.22	+0.4
2,123,835	-		Rv1874	0.22	+0.6
2,123,835	-		Rv1874	0.22	+0.1
2,123,879	+		Rv1874	0.28	-0.6
2,123,880	-		Rv1874	0.29	-1.1
2,123,892	+		Rv1874	0.30	+0.4
2,123,893	-		Rv1874	0.30	-0.3
2,123,893	-		Rv1874	0.30	+0.1
2,123,893	-		Rv1874	0.30	-0.1
2,123,910	+		Rv1874	0.33	-0.5
2,123,942	+		Rv1874	0.38	+1.4
2,123,943	-		Rv1874	0.38	+0.4
2,123,943	-		Rv1874	0.38	-0.2
2,123,943	-		Rv1874	0.38	-0.4
2,124,126	-		Rv1874	0.64	-0.3
2,124,341	+				-0.2
2,124,540	+		Rv1875	0.36	-3.3
2,124,540	+		Rv1875	0.36	+0.3
2,124,541	-		Rv1875	0.36	-0.8
2,124,567	-		Rv1875	0.42	-0.5
2,124,697	+		Rv1875	0.71	-1.0
2,124,698	-		Rv1875	0.71	-0.5
2,124,751	-		Rv1875	0.83	-0.6
2,124,811	-				-0.3
2,124,901	+				-1.9
2,124,902	-				+0.7
2,124,902	-				-0.2
2,124,902	-				+0.1
2,125,038	+				-1.6
2,125,090	-				-1.1
2,125,092	+				-1.5
2,125,092	+				-0.9
2,125,108	-				-0.0
2,125,126	+				-0.4
2,125,216	+				+1.4
2,125,217	-				-0.2
2,125,247	+				+0.2
2,125,247	+				+1.1
2,125,247	+				-0.6
2,125,320	+				+0.1
2,125,320	+				-0.3
2,125,320	+				+1.2
2,125,320	+				-0.9
2,125,320	+				-0.3
2,125,320	+				-0.3
2,125,320	+				-0.2
2,125,320	+				-0.2
2,125,320	+				-0.5
2,125,321	-				-0.1
2,125,321	-				-0.7
2,125,321	-				-0.1
2,125,321	-				+0.9
2,125,321	-				-0.4
2,125,321	-				-0.9
2,125,321	-				+0.1
2,125,321	-				-0.1
2,125,321	-				-1.7
2,125,321	-				+1.7
2,125,322	+				-1.4
2,125,323	-				+0.5
2,125,323	-				+1.2
2,125,323	-				-0.2
2,125,323	-				-0.1
2,125,329	+				-0.5
2,125,329	+				+0.0
2,125,330	-				+0.1
2,125,413	-		Rv1876	0.15	-0.4
2,125,550	+		Rv1876	0.44	-2.5
2,125,622	+		Rv1876	0.59	-0.1
2,125,736	+		Rv1876	0.82	+0.7
2,125,736	+		Rv1876	0.82	+0.0
2,125,736	+		Rv1876	0.82	-0.7
2,125,736	+		Rv1876	0.82	-1.9
2,125,736	+		Rv1876	0.82	-0.4
2,125,770	+		Rv1876	0.90	+0.1
2,125,770	+		Rv1876	0.90	+0.0
2,125,770	+		Rv1876	0.90	+2.9
2,125,770	+		Rv1876	0.90	-0.0
2,125,771	-		Rv1876	0.90	+0.2
2,125,771	-		Rv1876	0.90	-0.0
2,125,771	-		Rv1876	0.90	-0.1
2,125,771	-		Rv1876	0.90	-0.1
2,125,771	-		Rv1876	0.90	-0.3
2,125,771	-		Rv1876	0.90	+1.1