Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1523

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ofloxacin 0.8 ug/mL
1,716,774	+		Rv1522c	0.76	-0.1
1,716,774	+		Rv1522c	0.76	+0.1
1,716,774	+		Rv1522c	0.76	-1.1
1,716,774	+		Rv1522c	0.76	+0.4
1,716,775	-		Rv1522c	0.76	-0.7
1,716,775	-		Rv1522c	0.76	+0.1
1,716,784	-		Rv1522c	0.76	-1.8
1,716,791	+		Rv1522c	0.76	-0.0
1,716,807	+		Rv1522c	0.77	-0.0
1,716,841	+		Rv1522c	0.78	-0.4
1,716,841	+		Rv1522c	0.78	+0.3
1,716,842	-		Rv1522c	0.78	-2.9
1,716,967	-		Rv1522c	0.81	-0.7
1,717,263	-		Rv1522c	0.90	-0.5
1,717,567	+				+0.7
1,717,567	+				-2.5
1,717,623	+				+0.5
1,717,623	+				-0.6
1,717,624	-				-0.9
1,717,624	-				-0.0
1,717,624	-				-0.9
1,717,688	-				-0.8
1,717,688	-				-0.6
1,717,804	+		Rv1523	0.14	-0.6
1,717,804	+		Rv1523	0.14	+0.3
1,717,920	-		Rv1523	0.26	-0.5
1,717,920	-		Rv1523	0.26	-0.9
1,717,920	-		Rv1523	0.26	-0.2
1,717,924	-		Rv1523	0.26	-0.1
1,717,968	+		Rv1523	0.30	+0.5
1,717,968	+		Rv1523	0.30	+2.6
1,718,086	-		Rv1523	0.41	-0.3
1,718,101	-		Rv1523	0.43	-0.3
1,718,146	+		Rv1523	0.47	+0.1
1,718,147	-		Rv1523	0.47	-1.1
1,718,147	-		Rv1523	0.47	-0.3
1,718,181	+		Rv1523	0.51	+0.4
1,718,211	+		Rv1523	0.53	+0.2
1,718,211	+		Rv1523	0.53	-1.9
1,718,593	+				-0.8
1,718,593	+				-0.9
1,718,676	+				+0.6
1,718,677	-				-0.2
1,718,748	-				-0.4
1,718,748	-				+0.2
1,718,883	-		Rv1524	0.13	-0.3
1,719,065	+		Rv1524	0.27	-1.8
1,719,218	+		Rv1524	0.40	-1.0
1,719,309	+		Rv1524	0.47	+1.6