Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1450c

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ofloxacin 0.8 ug/mL
1,630,242	-				-0.6
1,630,242	-				+0.3
1,630,275	-				-1.6
1,630,306	+				-0.9
1,630,307	-				+0.6
1,630,393	-				+1.8
1,630,406	+				+1.7
1,630,407	-				-0.6
1,630,456	+				-1.8
1,630,457	-				-0.1
1,630,457	-				-0.9
1,630,640	-				+0.4
1,630,640	-				-0.2
1,630,700	+				+0.1
1,630,701	-				-1.3
1,630,701	-				+0.0
1,631,003	+				-0.4
1,631,004	-				-0.0
1,633,049	+		Rv1450c	0.60	-0.4
1,633,280	+		Rv1450c	0.66	-1.6
1,633,281	-		Rv1450c	0.66	-1.6
1,634,580	+				-0.1
1,634,580	+				-0.6
1,634,580	+				-0.8
1,634,580	+				+0.5
1,634,580	+				+0.1
1,634,580	+				-0.2
1,634,581	-				-0.2
1,634,581	-				-0.1
1,634,581	-				-0.1
1,634,849	+				-1.2
1,634,850	-				+0.0
1,634,974	+				-0.7
1,634,974	+				-0.3
1,634,975	-				-0.6
1,634,975	-				+0.6
1,634,986	+				-0.6
1,634,986	+				-1.4
1,634,989	+				+0.6
1,635,023	+				-0.6
1,635,070	+				+0.5