Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1363c

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1361c and Rv1362c are separated by 314 nucleotidesRv1362c and Rv1363c overlap by 4 nucleotidesRv1363c and Rv1364c are separated by 290 nucleotides Rv1361c: Rv1361c - PPE family protein PPE19, at 1,532,443 to 1,533,633 Rv1361c Rv1362c: Rv1362c - Possible membrane protein, at 1,533,948 to 1,534,610 Rv1362c Rv1363c: Rv1363c - Possible membrane protein, at 1,534,607 to 1,535,392 Rv1363c Rv1364c: Rv1364c - Possible sigma factor regulatory protein, at 1,535,683 to 1,537,644 Rv1364c Position (kb) 1534 1535 1536Strain fitness (log2 ratio) -4 -3 -2 -1 0 1 2 3 4at 1533.658 kb on + strandat 1533.662 kb on + strandat 1533.663 kb on - strandat 1533.717 kb on - strandat 1533.798 kb on + strandat 1533.798 kb on + strandat 1533.939 kb on + strandat 1533.949 kb on + strandat 1533.950 kb on - strandat 1533.950 kb on - strandat 1533.996 kb on + strandat 1534.046 kb on + strand, within Rv1362cat 1534.047 kb on - strand, within Rv1362cat 1534.099 kb on - strand, within Rv1362cat 1534.193 kb on - strand, within Rv1362cat 1534.360 kb on + strand, within Rv1362cat 1534.361 kb on - strand, within Rv1362cat 1534.363 kb on - strand, within Rv1362cat 1534.597 kb on - strandat 1534.638 kb on + strandat 1534.638 kb on + strandat 1534.638 kb on + strandat 1535.155 kb on - strand, within Rv1363cat 1535.155 kb on - strand, within Rv1363cat 1535.173 kb on - strand, within Rv1363cat 1535.199 kb on + strand, within Rv1363cat 1535.400 kb on - strandat 1535.413 kb on - strandat 1535.447 kb on + strandat 1535.461 kb on - strandat 1535.572 kb on + strandat 1535.572 kb on + strandat 1536.081 kb on + strand, within Rv1364cat 1536.082 kb on - strand, within Rv1364cat 1536.133 kb on + strand, within Rv1364c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ofloxacin 0.8 ug/mL
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1,533,658 + -0.5
1,533,662 + +0.5
1,533,663 - -0.2
1,533,717 - +4.1
1,533,798 + +0.5
1,533,798 + -2.4
1,533,939 + -1.9
1,533,949 + -0.6
1,533,950 - -0.3
1,533,950 - -4.5
1,533,996 + +0.3
1,534,046 + Rv1362c 0.15 -2.3
1,534,047 - Rv1362c 0.15 -0.4
1,534,099 - Rv1362c 0.23 -0.3
1,534,193 - Rv1362c 0.37 -0.4
1,534,360 + Rv1362c 0.62 -0.0
1,534,361 - Rv1362c 0.62 -0.2
1,534,363 - Rv1362c 0.63 -0.9
1,534,597 - +0.1
1,534,638 + -0.2
1,534,638 + +3.0
1,534,638 + -0.5
1,535,155 - Rv1363c 0.70 -0.9
1,535,155 - Rv1363c 0.70 -0.3
1,535,173 - Rv1363c 0.72 -0.6
1,535,199 + Rv1363c 0.75 -0.9
1,535,400 - -0.8
1,535,413 - -0.3
1,535,447 + -0.7
1,535,461 - -1.4
1,535,572 + +2.1
1,535,572 + -0.1
1,536,081 + Rv1364c 0.20 -1.2
1,536,082 - Rv1364c 0.20 +0.3
1,536,133 + Rv1364c 0.23 +1.6

Or see this region's nucleotide sequence