Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1359

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ofloxacin 0.8 ug/mL
1,529,181	-		Rv1358	0.74	-0.3
1,529,204	+		Rv1358	0.74	+0.2
1,529,205	-		Rv1358	0.75	-0.8
1,529,205	-		Rv1358	0.75	-0.4
1,529,302	-		Rv1358	0.77	+0.8
1,529,302	-		Rv1358	0.77	-1.8
1,529,606	+		Rv1358	0.86	-1.1
1,529,607	-		Rv1358	0.86	-0.3
1,529,753	+				+0.1
1,529,754	-				+0.3
1,529,999	-				+0.4
1,530,026	+				+2.6
1,530,026	+				+0.2
1,530,027	-				-0.3
1,530,027	-				+1.0
1,530,063	+				-0.9
1,530,063	+				+3.6
1,530,064	-				-0.7
1,530,090	-				+0.3
1,530,135	+				-1.3
1,530,272	-		Rv1359	0.13	-1.3
1,530,381	+		Rv1359	0.28	-1.2
1,530,575	+		Rv1359	0.53	+0.6
1,530,839	+		Rv1359	0.88	-0.9
1,530,949	-				-0.7
1,530,949	-				-0.2
1,531,064	+				+0.0
1,531,065	-				-0.6
1,531,179	-				-1.3
1,531,179	-				-1.2
1,531,248	+				-0.3
1,531,249	-				-0.3
1,531,336	-				+0.4
1,531,336	-				-0.1
1,531,593	-		Rv1360	0.24	-1.1
1,531,593	-		Rv1360	0.24	-0.6
1,531,777	+		Rv1360	0.42	-1.3
1,531,778	-		Rv1360	0.42	-0.0
1,531,914	+		Rv1360	0.55	-0.5
1,531,914	+		Rv1360	0.55	-0.1
1,531,914	+		Rv1360	0.55	+0.7
1,531,914	+		Rv1360	0.55	-0.7
1,531,914	+		Rv1360	0.55	-0.7
1,531,915	-		Rv1360	0.55	-1.4