Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1283c

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1281c and Rv1282c overlap by 4 nucleotidesRv1282c and Rv1283c overlap by 4 nucleotidesRv1283c and Rv1284 are separated by 206 nucleotidesRv1284 and Rv1285 are separated by 93 nucleotides Rv1281c: Rv1281c - Probable oligopeptide-transport ATP-binding protein ABC transporter OppD, at 1,433,433 to 1,435,271 Rv1281c Rv1282c: Rv1282c - Probable oligopeptide-transport integral membrane protein ABC transporter OppC, at 1,435,268 to 1,436,143 Rv1282c Rv1283c: Rv1283c - Probable oligopeptide-transport integral membrane protein ABC transporter OppB, at 1,436,140 to 1,437,117 Rv1283c Rv1284: Rv1284 - Beta-carbonic anhydrase, at 1,437,324 to 1,437,815 Rv1284 Rv1285: Rv1285 - Probable sulfate adenylyltransferase subunit 2 CysD, at 1,437,909 to 1,438,907 Rv1285 Position (kb) 1436 1437 1438Strain fitness (log2 ratio) -2 -1 0 1 2 3at 1435.187 kb on - strandat 1435.366 kb on + strand, within Rv1282cat 1435.367 kb on - strand, within Rv1282cat 1435.594 kb on + strand, within Rv1282cat 1435.595 kb on - strand, within Rv1282cat 1435.770 kb on - strand, within Rv1282cat 1436.007 kb on + strand, within Rv1282cat 1436.037 kb on + strand, within Rv1282cat 1436.097 kb on - strandat 1436.115 kb on - strandat 1436.175 kb on - strandat 1436.229 kb on + strandat 1436.489 kb on + strand, within Rv1283cat 1437.048 kb on - strandat 1437.084 kb on - strandat 1437.084 kb on - strandat 1437.107 kb on + strandat 1437.342 kb on + strandat 1437.342 kb on + strandat 1437.342 kb on + strandat 1437.681 kb on + strand, within Rv1284at 1437.834 kb on + strandat 1437.907 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ofloxacin 0.8 ug/mL
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1,435,187 - -0.7
1,435,366 + Rv1282c 0.11 -1.3
1,435,367 - Rv1282c 0.11 +3.0
1,435,594 + Rv1282c 0.37 +1.0
1,435,595 - Rv1282c 0.37 +1.6
1,435,770 - Rv1282c 0.57 -1.1
1,436,007 + Rv1282c 0.84 +1.0
1,436,037 + Rv1282c 0.88 +1.4
1,436,097 - -1.0
1,436,115 - -0.7
1,436,175 - -0.5
1,436,229 + +0.3
1,436,489 + Rv1283c 0.36 -0.9
1,437,048 - -0.3
1,437,084 - -1.8
1,437,084 - -0.4
1,437,107 + -0.4
1,437,342 + +0.1
1,437,342 + +1.0
1,437,342 + +0.2
1,437,681 + Rv1284 0.73 -1.5
1,437,834 + -0.6
1,437,907 - +0.0

Or see this region's nucleotide sequence