Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1256c

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1254 and Rv1255c overlap by 32 nucleotidesRv1255c and Rv1256c overlap by 1 nucleotidesRv1256c and Rv1257c are separated by 113 nucleotides Rv1254: Rv1254 - Probable acyltransferase, at 1,401,658 to 1,402,809 Rv1254 Rv1255c: Rv1255c - Probable transcriptional regulatory protein, at 1,402,778 to 1,403,386 Rv1255c Rv1256c: Rv1256c - Probable cytochrome P450 130 Cyp130, at 1,403,386 to 1,404,603 Rv1256c Rv1257c: Rv1257c - Probable oxidoreductase, at 1,404,717 to 1,406,084 Rv1257c Position (kb) 1403 1404 1405Strain fitness (log2 ratio) -2 -1 0 1at 1402.702 kb on + strandat 1402.964 kb on + strand, within Rv1255cat 1403.051 kb on - strand, within Rv1255cat 1403.194 kb on - strand, within Rv1255cat 1403.306 kb on - strand, within Rv1255cat 1403.429 kb on + strandat 1403.905 kb on + strand, within Rv1256cat 1404.141 kb on - strand, within Rv1256cat 1404.176 kb on - strand, within Rv1256cat 1404.464 kb on + strand, within Rv1256cat 1404.464 kb on + strand, within Rv1256cat 1404.467 kb on + strand, within Rv1256cat 1404.468 kb on - strand, within Rv1256cat 1404.474 kb on - strand, within Rv1256cat 1404.805 kb on + strandat 1404.944 kb on - strand, within Rv1257cat 1405.596 kb on + strand, within Rv1257cat 1405.596 kb on + strand, within Rv1257cat 1405.597 kb on - strand, within Rv1257cat 1405.597 kb on - strand, within Rv1257cat 1405.601 kb on - strand, within Rv1257c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ofloxacin 0.8 ug/mL
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1,402,702 + -0.4
1,402,964 + Rv1255c 0.31 +0.4
1,403,051 - Rv1255c 0.45 -2.5
1,403,194 - Rv1255c 0.68 +1.6
1,403,306 - Rv1255c 0.87 +0.6
1,403,429 + -0.6
1,403,905 + Rv1256c 0.43 -1.9
1,404,141 - Rv1256c 0.62 -1.8
1,404,176 - Rv1256c 0.65 -0.1
1,404,464 + Rv1256c 0.89 -0.7
1,404,464 + Rv1256c 0.89 -1.0
1,404,467 + Rv1256c 0.89 -0.6
1,404,468 - Rv1256c 0.89 -0.9
1,404,474 - Rv1256c 0.89 -0.4
1,404,805 + -0.3
1,404,944 - Rv1257c 0.17 -0.3
1,405,596 + Rv1257c 0.64 +0.7
1,405,596 + Rv1257c 0.64 -0.4
1,405,597 - Rv1257c 0.64 +0.3
1,405,597 - Rv1257c 0.64 -1.2
1,405,601 - Rv1257c 0.65 +0.8

Or see this region's nucleotide sequence