Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1020

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ofloxacin 0.8 ug/mL
1,138,211	+				-0.3
1,138,212	-				-1.1
1,138,424	+		Rv1019	0.18	-0.9
1,138,424	+		Rv1019	0.18	-0.8
1,138,425	-		Rv1019	0.19	-1.4
1,138,441	+		Rv1019	0.21	-1.0
1,138,441	+		Rv1019	0.21	-1.3
1,138,471	+		Rv1019	0.26	-0.6
1,138,585	+		Rv1019	0.45	+0.1
1,138,585	+		Rv1019	0.45	+0.2
1,138,586	-		Rv1019	0.46	-0.8
1,138,586	-		Rv1019	0.46	-0.5
1,138,753	+		Rv1019	0.74	-0.4
1,138,753	+		Rv1019	0.74	-0.1
1,138,754	-		Rv1019	0.74	-1.4
1,138,895	+				-0.6
1,138,953	-				-0.3
1,138,953	-				+0.1
1,138,953	-				-0.2
1,139,362	-		Rv1020	0.11	-3.6
1,139,492	+		Rv1020	0.14	-2.4
1,139,492	+		Rv1020	0.14	-1.1
1,139,492	+		Rv1020	0.14	-1.0
1,139,493	-		Rv1020	0.14	-1.2
1,139,495	-		Rv1020	0.14	-1.2
1,139,507	-		Rv1020	0.15	-0.7
1,139,507	-		Rv1020	0.15	-2.1
1,140,219	+		Rv1020	0.34	+1.9
1,140,220	-		Rv1020	0.34	-1.3
1,140,220	-		Rv1020	0.34	-0.1
1,140,626	+		Rv1020	0.45	-1.0
1,140,627	-		Rv1020	0.45	-1.2
1,140,674	+		Rv1020	0.46	-2.3
1,140,674	+		Rv1020	0.46	-1.9
1,140,675	-		Rv1020	0.46	-0.9
1,140,711	-		Rv1020	0.47	-0.9
1,140,711	-		Rv1020	0.47	-2.1
1,140,824	+		Rv1020	0.50	-1.8
1,141,550	+		Rv1020	0.70	-0.6
1,141,842	-		Rv1020	0.78	-0.7
1,141,856	+		Rv1020	0.78	-0.8
1,141,857	-		Rv1020	0.78	+0.9
1,141,857	-		Rv1020	0.78	+0.9
1,141,960	-		Rv1020	0.81	-2.4
1,142,033	+		Rv1020	0.83	-1.2
1,142,033	+		Rv1020	0.83	-1.7
1,142,034	-		Rv1020	0.83	-1.0
1,142,034	-		Rv1020	0.83	+0.4
1,142,067	-		Rv1020	0.84	-1.4
1,142,079	-		Rv1020	0.84	-0.3
1,142,174	+		Rv1020	0.87	-0.1
1,142,265	+		Rv1020	0.89	+0.7
1,142,266	-		Rv1020	0.89	-1.4
1,142,276	+		Rv1020	0.89	-1.0
1,142,277	-		Rv1020	0.89	-0.2
1,142,441	+				-0.3
1,142,456	+				-0.8
1,142,457	-				-1.2
1,142,600	-				-0.8
1,142,600	-				-1.1
1,142,602	-				-0.1
1,142,602	-				-1.1
1,142,602	-				-3.3
1,142,602	-				-1.1
1,142,653	+				-0.4
1,142,654	-				-1.0
1,142,752	+				-0.1
1,142,869	-		Rv1021	0.20	-0.8
1,143,032	-		Rv1021	0.37	+0.4