Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0986

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0984 and Rv0985c are separated by 19 nucleotidesRv0985c and Rv0986 are separated by 322 nucleotidesRv0986 and Rv0987 overlap by 8 nucleotides Rv0984: Rv0984 - Possible pterin-4-alpha-carbinolamine dehydratase MoaB2 (PHS) (4-alpha-hydroxy-tetrahydropterin dehydratase) (pterin-4-a-carbinolamine dehydratase) (phenylalanine hydroxylase-stimulating protein) (PHS) (pterin carbinolamine dehydratase) (PCD), at 1,100,460 to 1,101,005 Rv0984 Rv0985c: Rv0985c - Possible large-conductance ion mechanosensitive channel MscL, at 1,101,025 to 1,101,480 Rv0985c Rv0986: Rv0986 - Probable adhesion component transport ATP-binding protein ABC transporter, at 1,101,803 to 1,102,549 Rv0986 Rv0987: Rv0987 - Probable adhesion component transport transmembrane protein ABC transporter, at 1,102,542 to 1,105,109 Rv0987 Position (kb) 1101 1102 1103Strain fitness (log2 ratio) -2 -1 0 1 2at 1100.925 kb on + strand, within Rv0984at 1101.190 kb on + strand, within Rv0985cat 1101.190 kb on + strand, within Rv0985cat 1101.191 kb on - strand, within Rv0985cat 1101.200 kb on + strand, within Rv0985cat 1101.214 kb on + strand, within Rv0985cat 1101.215 kb on - strand, within Rv0985cat 1101.215 kb on - strand, within Rv0985cat 1101.221 kb on + strand, within Rv0985cat 1101.363 kb on + strand, within Rv0985cat 1101.363 kb on + strand, within Rv0985cat 1101.364 kb on - strand, within Rv0985cat 1101.444 kb on + strandat 1101.445 kb on - strandat 1101.800 kb on + strandat 1101.801 kb on - strandat 1101.833 kb on - strandat 1102.417 kb on + strand, within Rv0986at 1102.459 kb on - strand, within Rv0986at 1102.477 kb on - strandat 1102.840 kb on - strand, within Rv0987at 1103.438 kb on - strand, within Rv0987at 1103.452 kb on + strand, within Rv0987at 1103.464 kb on + strand, within Rv0987

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ofloxacin 0.8 ug/mL
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1,100,925 + Rv0984 0.85 +0.4
1,101,190 + Rv0985c 0.36 -0.2
1,101,190 + Rv0985c 0.36 +1.4
1,101,191 - Rv0985c 0.36 +2.1
1,101,200 + Rv0985c 0.38 +0.3
1,101,214 + Rv0985c 0.41 +0.1
1,101,215 - Rv0985c 0.42 +1.4
1,101,215 - Rv0985c 0.42 -1.2
1,101,221 + Rv0985c 0.43 -1.9
1,101,363 + Rv0985c 0.74 -0.9
1,101,363 + Rv0985c 0.74 -0.0
1,101,364 - Rv0985c 0.74 +1.4
1,101,444 + +1.4
1,101,445 - +0.1
1,101,800 + +0.9
1,101,801 - +1.2
1,101,833 - +0.9
1,102,417 + Rv0986 0.82 -1.3
1,102,459 - Rv0986 0.88 -0.6
1,102,477 - -0.2
1,102,840 - Rv0987 0.12 -1.2
1,103,438 - Rv0987 0.35 +0.4
1,103,452 + Rv0987 0.35 -0.4
1,103,464 + Rv0987 0.36 -0.5

Or see this region's nucleotide sequence