Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0961

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0959 and Rv0959A are separated by 53 nucleotidesRv0959A and Rv0960 overlap by 4 nucleotidesRv0960 and Rv0961 are separated by 145 nucleotidesRv0961 and Rv0962c are separated by 18 nucleotidesRv0962c and Rv0963c are separated by 182 nucleotides Rv0959: Rv0959 - Conserved hypothetical protein, at 1,071,255 to 1,073,273 Rv0959 Rv0959A: Rv0959A - Possible antitoxin VapB9, at 1,073,327 to 1,073,548 Rv0959A Rv0960: Rv0960 - Possible toxin VapC9, at 1,073,545 to 1,073,928 Rv0960 Rv0961: Rv0961 - Probable integral membrane protein, at 1,074,074 to 1,074,421 Rv0961 Rv0962c: Rv0962c - Possible lipoprotein LprP, at 1,074,440 to 1,075,114 Rv0962c Rv0963c: Rv0963c - Conserved hypothetical protein, at 1,075,297 to 1,076,097 Rv0963c Position (kb) 1074 1075Strain fitness (log2 ratio) -3 -2 -1 0 1at 1073.339 kb on + strandat 1073.339 kb on + strandat 1073.782 kb on - strand, within Rv0960at 1073.825 kb on - strand, within Rv0960at 1073.825 kb on - strand, within Rv0960at 1073.825 kb on - strand, within Rv0960at 1073.825 kb on - strand, within Rv0960at 1073.957 kb on + strandat 1073.971 kb on - strandat 1074.146 kb on + strand, within Rv0961at 1074.146 kb on + strand, within Rv0961at 1074.146 kb on + strand, within Rv0961at 1074.147 kb on - strand, within Rv0961at 1074.192 kb on + strand, within Rv0961at 1074.192 kb on + strand, within Rv0961at 1074.245 kb on + strand, within Rv0961at 1074.392 kb on + strandat 1074.393 kb on - strandat 1074.393 kb on - strandat 1074.445 kb on - strandat 1074.478 kb on - strandat 1074.478 kb on - strandat 1074.576 kb on + strand, within Rv0962cat 1074.576 kb on + strand, within Rv0962cat 1074.577 kb on - strand, within Rv0962cat 1074.577 kb on - strand, within Rv0962cat 1074.577 kb on - strand, within Rv0962cat 1074.582 kb on + strand, within Rv0962cat 1074.620 kb on + strand, within Rv0962cat 1074.791 kb on + strand, within Rv0962cat 1074.791 kb on + strand, within Rv0962cat 1074.791 kb on + strand, within Rv0962cat 1075.036 kb on + strand, within Rv0962cat 1075.036 kb on + strand, within Rv0962cat 1075.037 kb on - strand, within Rv0962cat 1075.049 kb on - strandat 1075.122 kb on - strandat 1075.136 kb on - strandat 1075.241 kb on + strandat 1075.275 kb on + strandat 1075.298 kb on + strandat 1075.298 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ofloxacin 0.8 ug/mL
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1,073,339 + -0.6
1,073,339 + -0.8
1,073,782 - Rv0960 0.62 -1.0
1,073,825 - Rv0960 0.73 -1.0
1,073,825 - Rv0960 0.73 -0.5
1,073,825 - Rv0960 0.73 +0.2
1,073,825 - Rv0960 0.73 -0.3
1,073,957 + -1.5
1,073,971 - +1.0
1,074,146 + Rv0961 0.21 -0.8
1,074,146 + Rv0961 0.21 -0.6
1,074,146 + Rv0961 0.21 -0.7
1,074,147 - Rv0961 0.21 -0.0
1,074,192 + Rv0961 0.34 -3.7
1,074,192 + Rv0961 0.34 -0.2
1,074,245 + Rv0961 0.49 -0.8
1,074,392 + -0.6
1,074,393 - -1.2
1,074,393 - +0.5
1,074,445 - +0.6
1,074,478 - +0.3
1,074,478 - -0.5
1,074,576 + Rv0962c 0.20 +0.0
1,074,576 + Rv0962c 0.20 +0.7
1,074,577 - Rv0962c 0.20 -0.6
1,074,577 - Rv0962c 0.20 +0.1
1,074,577 - Rv0962c 0.20 -0.0
1,074,582 + Rv0962c 0.21 -0.4
1,074,620 + Rv0962c 0.27 -0.1
1,074,791 + Rv0962c 0.52 -1.2
1,074,791 + Rv0962c 0.52 -1.8
1,074,791 + Rv0962c 0.52 +0.1
1,075,036 + Rv0962c 0.88 -1.0
1,075,036 + Rv0962c 0.88 -0.7
1,075,037 - Rv0962c 0.88 +0.8
1,075,049 - -0.2
1,075,122 - -1.0
1,075,136 - -0.0
1,075,241 + -0.6
1,075,275 + -0.7
1,075,298 + -0.9
1,075,298 + -0.1

Or see this region's nucleotide sequence