Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0629c

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0628c and Rv0629c are separated by 92 nucleotidesRv0629c and Rv0630c overlap by 4 nucleotides Rv0628c: Rv0628c - Conserved hypothetical protein, at 718,761 to 719,912 Rv0628c Rv0629c: Rv0629c - Probable exonuclease V (alpha chain) RecD (exodeoxyribonuclease V alpha chain) (exodeoxyribonuclease V polypeptide), at 720,005 to 721,732 Rv0629c Rv0630c: Rv0630c - Probable exonuclease V (beta chain) RecB (exodeoxyribonuclease V beta chain)(exodeoxyribonuclease V polypeptide) (chi-specific endonuclease), at 721,729 to 725,013 Rv0630c Position (kb) 720 721 722Strain fitness (log2 ratio) -1 0 1 2 3 4at 719.305 kb on + strand, within Rv0628cat 719.305 kb on + strand, within Rv0628cat 719.305 kb on + strand, within Rv0628cat 719.306 kb on - strand, within Rv0628cat 719.306 kb on - strand, within Rv0628cat 719.306 kb on - strand, within Rv0628cat 719.522 kb on - strand, within Rv0628cat 719.948 kb on - strandat 720.354 kb on + strand, within Rv0629cat 720.355 kb on - strand, within Rv0629cat 720.376 kb on - strand, within Rv0629cat 721.713 kb on + strandat 721.868 kb on + strandat 722.045 kb on + strandat 722.160 kb on - strand, within Rv0630c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ofloxacin 0.8 ug/mL
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719,305 + Rv0628c 0.47 -0.3
719,305 + Rv0628c 0.47 +0.5
719,305 + Rv0628c 0.47 -0.9
719,306 - Rv0628c 0.47 +0.0
719,306 - Rv0628c 0.47 +0.8
719,306 - Rv0628c 0.47 -0.7
719,522 - Rv0628c 0.66 -0.4
719,948 - -0.6
720,354 + Rv0629c 0.20 -0.4
720,355 - Rv0629c 0.20 -1.2
720,376 - Rv0629c 0.21 -1.6
721,713 + +3.8
721,868 + +0.7
722,045 + -0.2
722,160 - Rv0630c 0.13 +0.7

Or see this region's nucleotide sequence