Experiment: 7H9 with Ofloxacin 0.8 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0497 and Rv0498 are separated by 15 nucleotides Rv0498 and Rv0499 are separated by 15 nucleotides Rv0499 and Rv0500 are separated by 24 nucleotides
Rv0497: Rv0497 - Probable conserved transmembrane protein, at 587,377 to 588,309
Rv0497
Rv0498: Rv0498 - Conserved hypothetical protein, at 588,325 to 589,167
Rv0498
Rv0499: Rv0499 - Conserved hypothetical protein, at 589,183 to 590,058
Rv0499
Rv0500: Rv0500 - Probable pyrroline-5-carboxylate reductase ProC (P5CR) (P5C reductase), at 590,083 to 590,970
Rv0500
Position (kb) 589
590
591 Strain fitness (log2 ratio) -1
0
1
2 at 588.689 kb on + strand, within Rv0498 at 588.690 kb on - strand, within Rv0498 at 588.690 kb on - strand, within Rv0498 at 588.786 kb on + strand, within Rv0498 at 588.786 kb on + strand, within Rv0498 at 588.787 kb on - strand, within Rv0498 at 588.787 kb on - strand, within Rv0498 at 588.835 kb on + strand, within Rv0498 at 588.835 kb on + strand, within Rv0498 at 588.836 kb on - strand, within Rv0498 at 588.866 kb on - strand, within Rv0498 at 588.866 kb on - strand, within Rv0498 at 589.169 kb on - strand at 589.182 kb on + strand at 589.182 kb on + strand at 589.183 kb on - strand at 589.700 kb on + strand, within Rv0499 at 589.700 kb on + strand, within Rv0499 at 589.885 kb on - strand, within Rv0499 at 590.057 kb on - strand at 591.042 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Ofloxacin 0.8 ug/mL remove 588,689 + Rv0498 0.43 -0.4 588,690 - Rv0498 0.43 -1.2 588,690 - Rv0498 0.43 +0.7 588,786 + Rv0498 0.55 -0.1 588,786 + Rv0498 0.55 -0.0 588,787 - Rv0498 0.55 -0.6 588,787 - Rv0498 0.55 -0.3 588,835 + Rv0498 0.60 -0.4 588,835 + Rv0498 0.60 -0.1 588,836 - Rv0498 0.61 +0.5 588,866 - Rv0498 0.64 +0.2 588,866 - Rv0498 0.64 +2.2 589,169 - +0.7 589,182 + +0.4 589,182 + +0.3 589,183 - +0.3 589,700 + Rv0499 0.59 -1.0 589,700 + Rv0499 0.59 -0.6 589,885 - Rv0499 0.80 -1.4 590,057 - +0.6 591,042 + -1.0
Or see this region's nucleotide sequence