Experiment: 7H9 with Ofloxacin 0.8 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0462 and Rv0463 are separated by 7 nucleotides Rv0463 and Rv0464c are separated by 3 nucleotides Rv0464c and Rv0465c overlap by 4 nucleotides
Rv0462: Rv0462 - Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphorase), at 552,614 to 554,008
Rv0462
Rv0463: Rv0463 - Probable conserved membrane protein, at 554,016 to 554,309
Rv0463
Rv0464c: Rv0464c - Conserved protein, at 554,313 to 554,885
Rv0464c
Rv0465c: Rv0465c - Probable transcriptional regulatory protein, at 554,882 to 556,306
Rv0465c
Position (kb) 554
555 Strain fitness (log2 ratio) -2
-1
0
1
2 at 554.085 kb on + strand, within Rv0463 at 554.085 kb on + strand, within Rv0463 at 554.085 kb on + strand, within Rv0463 at 554.086 kb on - strand, within Rv0463 at 554.159 kb on - strand, within Rv0463 at 554.159 kb on - strand, within Rv0463 at 554.301 kb on + strand at 554.314 kb on + strand at 554.315 kb on - strand at 554.315 kb on - strand at 554.487 kb on + strand, within Rv0464c at 554.584 kb on - strand, within Rv0464c at 554.641 kb on - strand, within Rv0464c at 554.713 kb on + strand, within Rv0464c at 554.713 kb on + strand, within Rv0464c at 554.737 kb on + strand, within Rv0464c at 554.737 kb on + strand, within Rv0464c at 554.738 kb on - strand, within Rv0464c at 554.885 kb on + strand at 554.885 kb on + strand at 554.886 kb on - strand at 554.886 kb on - strand at 555.011 kb on - strand at 555.026 kb on - strand, within Rv0465c at 555.026 kb on - strand, within Rv0465c at 555.061 kb on - strand, within Rv0465c at 555.116 kb on - strand, within Rv0465c at 555.129 kb on + strand, within Rv0465c at 555.171 kb on + strand, within Rv0465c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Ofloxacin 0.8 ug/mL remove 554,085 + Rv0463 0.23 -0.8 554,085 + Rv0463 0.23 -2.3 554,085 + Rv0463 0.23 -1.6 554,086 - Rv0463 0.24 +0.2 554,159 - Rv0463 0.49 +0.7 554,159 - Rv0463 0.49 -0.7 554,301 + -0.9 554,314 + -0.4 554,315 - +2.3 554,315 - -0.2 554,487 + Rv0464c 0.30 -0.1 554,584 - Rv0464c 0.47 -1.1 554,641 - Rv0464c 0.57 -2.5 554,713 + Rv0464c 0.70 -0.9 554,713 + Rv0464c 0.70 +0.8 554,737 + Rv0464c 0.74 +0.2 554,737 + Rv0464c 0.74 -0.3 554,738 - Rv0464c 0.74 -2.0 554,885 + -1.1 554,885 + -0.2 554,886 - -0.6 554,886 - -0.7 555,011 - +0.3 555,026 - Rv0465c 0.10 +0.4 555,026 - Rv0465c 0.10 +0.1 555,061 - Rv0465c 0.13 -0.1 555,116 - Rv0465c 0.16 -1.2 555,129 + Rv0465c 0.17 -0.4 555,171 + Rv0465c 0.20 +0.2
Or see this region's nucleotide sequence