Experiment: 7H9 with Ofloxacin 0.8 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0447c and Rv0448c overlap by 4 nucleotides Rv0448c and Rv0449c are separated by 59 nucleotides Rv0449c and Rv0450c are separated by 39 nucleotides
Rv0447c: Rv0447c - Probable cyclopropane-fatty-acyl-phospholipid synthase UfaA1 (cyclopropane fatty acid synthase) (CFA synthase), at 535,224 to 536,507
Rv0447c
Rv0448c: Rv0448c - Conserved hypothetical protein, at 536,504 to 537,169
Rv0448c
Rv0449c: Rv0449c - Conserved hypothetical protein, at 537,229 to 538,548
Rv0449c
Rv0450c: Rv0450c - Probable conserved transmembrane transport protein MmpL4, at 538,588 to 541,491
Rv0450c
Position (kb) 537
538
539 Strain fitness (log2 ratio) -4
-3
-2
-1
0
1 at 536.739 kb on - strand, within Rv0448c at 536.745 kb on + strand, within Rv0448c at 536.746 kb on - strand, within Rv0448c at 536.746 kb on - strand, within Rv0448c at 536.746 kb on - strand, within Rv0448c at 536.779 kb on - strand, within Rv0448c at 536.779 kb on - strand, within Rv0448c at 536.820 kb on - strand, within Rv0448c at 536.826 kb on + strand, within Rv0448c at 536.826 kb on + strand, within Rv0448c at 536.928 kb on + strand, within Rv0448c at 537.029 kb on - strand, within Rv0448c at 537.132 kb on + strand at 537.133 kb on - strand at 537.142 kb on - strand at 537.142 kb on - strand at 537.142 kb on - strand at 537.205 kb on - strand at 537.536 kb on + strand, within Rv0449c at 537.575 kb on + strand, within Rv0449c at 537.575 kb on + strand, within Rv0449c at 537.866 kb on + strand, within Rv0449c at 537.866 kb on + strand, within Rv0449c at 537.866 kb on + strand, within Rv0449c at 537.866 kb on + strand, within Rv0449c at 537.866 kb on + strand, within Rv0449c at 537.867 kb on - strand, within Rv0449c at 537.953 kb on + strand, within Rv0449c at 537.954 kb on - strand, within Rv0449c at 538.037 kb on + strand, within Rv0449c at 538.038 kb on - strand, within Rv0449c at 538.170 kb on - strand, within Rv0449c at 538.170 kb on - strand, within Rv0449c at 538.230 kb on - strand, within Rv0449c at 538.230 kb on - strand, within Rv0449c at 538.325 kb on + strand, within Rv0449c at 538.326 kb on - strand, within Rv0449c at 538.407 kb on - strand, within Rv0449c at 538.407 kb on - strand, within Rv0449c at 538.448 kb on + strand at 538.449 kb on - strand at 538.449 kb on - strand at 538.481 kb on + strand at 538.481 kb on + strand at 538.481 kb on + strand at 538.555 kb on + strand at 538.712 kb on - strand at 538.921 kb on + strand, within Rv0450c at 538.922 kb on - strand, within Rv0450c at 539.475 kb on + strand, within Rv0450c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Ofloxacin 0.8 ug/mL remove 536,739 - Rv0448c 0.35 -0.1 536,745 + Rv0448c 0.36 -0.7 536,746 - Rv0448c 0.36 +0.7 536,746 - Rv0448c 0.36 +0.5 536,746 - Rv0448c 0.36 +0.1 536,779 - Rv0448c 0.41 -0.0 536,779 - Rv0448c 0.41 -0.8 536,820 - Rv0448c 0.47 -4.1 536,826 + Rv0448c 0.48 -0.6 536,826 + Rv0448c 0.48 -0.0 536,928 + Rv0448c 0.64 -0.8 537,029 - Rv0448c 0.79 -2.1 537,132 + -0.6 537,133 - +0.1 537,142 - -0.8 537,142 - +0.7 537,142 - +0.2 537,205 - +0.1 537,536 + Rv0449c 0.23 -0.5 537,575 + Rv0449c 0.26 -0.7 537,575 + Rv0449c 0.26 -1.6 537,866 + Rv0449c 0.48 -0.9 537,866 + Rv0449c 0.48 +0.3 537,866 + Rv0449c 0.48 +1.0 537,866 + Rv0449c 0.48 +0.6 537,866 + Rv0449c 0.48 -1.1 537,867 - Rv0449c 0.48 -0.8 537,953 + Rv0449c 0.55 -0.3 537,954 - Rv0449c 0.55 -0.1 538,037 + Rv0449c 0.61 +0.3 538,038 - Rv0449c 0.61 +0.3 538,170 - Rv0449c 0.71 -0.2 538,170 - Rv0449c 0.71 -0.3 538,230 - Rv0449c 0.76 -0.5 538,230 - Rv0449c 0.76 +1.0 538,325 + Rv0449c 0.83 -0.3 538,326 - Rv0449c 0.83 +0.2 538,407 - Rv0449c 0.89 -3.3 538,407 - Rv0449c 0.89 -0.2 538,448 + -0.8 538,449 - +0.3 538,449 - -0.2 538,481 + -2.1 538,481 + -0.4 538,481 + -0.0 538,555 + -0.1 538,712 - -0.3 538,921 + Rv0450c 0.11 -2.1 538,922 - Rv0450c 0.12 -0.9 539,475 + Rv0450c 0.31 -0.0
Or see this region's nucleotide sequence