Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0367c

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0365c and Rv0366c are separated by 24 nucleotidesRv0366c and Rv0367c are separated by 28 nucleotidesRv0367c and Rv0368c are separated by 80 nucleotides Rv0365c: Rv0365c - Conserved protein, at 443,067 to 444,197 Rv0365c Rv0366c: Rv0366c - Conserved hypothetical protein, at 444,222 to 444,815 Rv0366c Rv0367c: Rv0367c - Hypothetical protein, at 444,844 to 445,233 Rv0367c Rv0368c: Rv0368c - Conserved hypothetical protein, at 445,314 to 446,525 Rv0368c Position (kb) 444 445 446Strain fitness (log2 ratio) -2 -1 0 1 2at 443.857 kb on - strand, within Rv0365cat 443.915 kb on - strand, within Rv0365cat 443.915 kb on - strand, within Rv0365cat 443.917 kb on + strand, within Rv0365cat 443.918 kb on - strand, within Rv0365cat 443.918 kb on - strand, within Rv0365cat 443.918 kb on - strand, within Rv0365cat 443.918 kb on - strand, within Rv0365cat 444.052 kb on + strand, within Rv0365cat 444.223 kb on + strandat 444.224 kb on - strandat 444.224 kb on - strandat 444.243 kb on - strandat 444.522 kb on + strand, within Rv0366cat 444.522 kb on + strand, within Rv0366cat 444.522 kb on + strand, within Rv0366cat 444.661 kb on + strand, within Rv0366cat 444.661 kb on + strand, within Rv0366cat 444.661 kb on + strand, within Rv0366cat 444.985 kb on - strand, within Rv0367cat 445.263 kb on + strandat 445.391 kb on - strandat 445.566 kb on + strand, within Rv0368cat 445.622 kb on + strand, within Rv0368cat 445.646 kb on + strand, within Rv0368cat 445.647 kb on - strand, within Rv0368cat 445.662 kb on + strand, within Rv0368cat 445.662 kb on + strand, within Rv0368cat 445.663 kb on - strand, within Rv0368cat 445.663 kb on - strand, within Rv0368cat 445.663 kb on - strand, within Rv0368cat 445.663 kb on - strand, within Rv0368cat 445.663 kb on - strand, within Rv0368cat 445.663 kb on - strand, within Rv0368cat 445.663 kb on - strand, within Rv0368cat 445.700 kb on + strand, within Rv0368cat 445.701 kb on - strand, within Rv0368cat 445.786 kb on + strand, within Rv0368cat 445.786 kb on + strand, within Rv0368cat 445.786 kb on + strand, within Rv0368cat 445.787 kb on - strand, within Rv0368cat 445.787 kb on - strand, within Rv0368cat 445.787 kb on - strand, within Rv0368cat 445.798 kb on + strand, within Rv0368cat 445.798 kb on + strand, within Rv0368cat 446.147 kb on + strand, within Rv0368cat 446.147 kb on + strand, within Rv0368cat 446.148 kb on - strand, within Rv0368cat 446.148 kb on - strand, within Rv0368c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ofloxacin 0.8 ug/mL
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443,857 - Rv0365c 0.70 +1.4
443,915 - Rv0365c 0.75 -0.3
443,915 - Rv0365c 0.75 -0.7
443,917 + Rv0365c 0.75 +0.2
443,918 - Rv0365c 0.75 +0.1
443,918 - Rv0365c 0.75 +0.5
443,918 - Rv0365c 0.75 -0.7
443,918 - Rv0365c 0.75 -0.8
444,052 + Rv0365c 0.87 -0.2
444,223 + +0.3
444,224 - +0.7
444,224 - -0.9
444,243 - -0.5
444,522 + Rv0366c 0.51 +1.3
444,522 + Rv0366c 0.51 +1.6
444,522 + Rv0366c 0.51 -0.0
444,661 + Rv0366c 0.74 +0.0
444,661 + Rv0366c 0.74 -0.0
444,661 + Rv0366c 0.74 -0.1
444,985 - Rv0367c 0.36 -0.8
445,263 + +0.0
445,391 - -2.1
445,566 + Rv0368c 0.21 +0.5
445,622 + Rv0368c 0.25 +0.2
445,646 + Rv0368c 0.27 -0.4
445,647 - Rv0368c 0.27 -0.3
445,662 + Rv0368c 0.29 +0.9
445,662 + Rv0368c 0.29 -0.2
445,663 - Rv0368c 0.29 -1.1
445,663 - Rv0368c 0.29 -2.3
445,663 - Rv0368c 0.29 +0.2
445,663 - Rv0368c 0.29 -0.9
445,663 - Rv0368c 0.29 -2.4
445,663 - Rv0368c 0.29 -0.5
445,663 - Rv0368c 0.29 -0.8
445,700 + Rv0368c 0.32 -0.2
445,701 - Rv0368c 0.32 +0.4
445,786 + Rv0368c 0.39 +0.5
445,786 + Rv0368c 0.39 +0.2
445,786 + Rv0368c 0.39 -0.0
445,787 - Rv0368c 0.39 -1.8
445,787 - Rv0368c 0.39 -0.7
445,787 - Rv0368c 0.39 +1.8
445,798 + Rv0368c 0.40 -0.6
445,798 + Rv0368c 0.40 -1.6
446,147 + Rv0368c 0.69 -0.5
446,147 + Rv0368c 0.69 +1.4
446,148 - Rv0368c 0.69 -0.1
446,148 - Rv0368c 0.69 +0.9

Or see this region's nucleotide sequence