Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3579c

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv3578 and Rv3579c are separated by 41 nucleotidesRv3579c and Rv3580c are separated by 0 nucleotides Rv3578: Rv3578 - Possible arsenical pump integral membrane protein ArsB2, at 4,020,142 to 4,021,383 Rv3578 Rv3579c: Rv3579c - Possible tRNA/rRNA methyltransferase, at 4,021,425 to 4,022,393 Rv3579c Rv3580c: Rv3580c - Cysteinyl-tRNA synthetase 1 CysS1 (cysteine--tRNA ligase 1) (CYSRS 1) (cysteine translase), at 4,022,394 to 4,023,803 Rv3580c Position (kb) 4021 4022 4023Strain fitness (log2 ratio) -1 0 1 2 3at 4020.556 kb on + strand, within Rv3578at 4020.557 kb on - strand, within Rv3578at 4020.628 kb on + strand, within Rv3578at 4020.628 kb on + strand, within Rv3578at 4020.706 kb on + strand, within Rv3578at 4020.706 kb on + strand, within Rv3578at 4020.707 kb on - strand, within Rv3578at 4020.740 kb on + strand, within Rv3578at 4021.220 kb on - strand, within Rv3578at 4022.396 kb on - strand

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ofloxacin 0.8 ug/mL
remove
4,020,556 + Rv3578 0.33 +0.2
4,020,557 - Rv3578 0.33 +1.2
4,020,628 + Rv3578 0.39 -0.8
4,020,628 + Rv3578 0.39 +3.1
4,020,706 + Rv3578 0.45 -0.7
4,020,706 + Rv3578 0.45 +0.6
4,020,707 - Rv3578 0.45 +0.2
4,020,740 + Rv3578 0.48 -1.4
4,021,220 - Rv3578 0.87 -1.4
4,022,396 - -0.4

Or see this region's nucleotide sequence