Experiment: 7H9 with Ofloxacin 0.8 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv2847c and Rv2848c are separated by 276 nucleotides Rv2848c and Rv2849c overlap by 1 nucleotides Rv2849c and Rv2850c are separated by 20 nucleotides
Rv2847c: Rv2847c - Possible multifunctional enzyme siroheme synthase CysG: uroporphyrin-III C-methyltransferase (urogen III methylase) (SUMT) (uroporphyrinogen III methylase) (UROM) + precorrin-2 oxidase + ferrochelatase, at 3,154,654 to 3,155,871
Rv2847c
Rv2848c: Rv2848c - Probable cobyrinic acid A,C-diamide synthase CobB, at 3,156,148 to 3,157,521
Rv2848c
Rv2849c: Rv2849c - Probable cob(I)alamin adenosyltransferase CobO (corrinoid adenosyltransferase) (corrinoid adotransferase activity), at 3,157,521 to 3,158,144
Rv2849c
Rv2850c: Rv2850c - Possible magnesium chelatase, at 3,158,165 to 3,160,054
Rv2850c
Position (kb)
3156
3157
3158 Strain fitness (log2 ratio)
-2
-1
0
1
2 at 3155.882 kb on + strand at 3155.882 kb on + strand at 3155.883 kb on - strand at 3156.106 kb on + strand at 3156.107 kb on - strand at 3156.162 kb on + strand at 3156.163 kb on - strand at 3156.222 kb on + strand at 3156.223 kb on - strand at 3156.637 kb on - strand, within Rv2848c at 3156.941 kb on + strand, within Rv2848c at 3156.941 kb on + strand, within Rv2848c at 3156.942 kb on - strand, within Rv2848c at 3156.942 kb on - strand, within Rv2848c at 3156.942 kb on - strand, within Rv2848c at 3157.312 kb on - strand, within Rv2848c at 3157.402 kb on + strand at 3157.721 kb on - strand, within Rv2849c at 3157.841 kb on + strand, within Rv2849c at 3157.842 kb on - strand, within Rv2849c at 3158.152 kb on + strand at 3158.153 kb on - strand at 3158.157 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Ofloxacin 0.8 ug/mL remove 3,155,882 + -0.6 3,155,882 + -0.4 3,155,883 - -0.2 3,156,106 + +0.1 3,156,107 - +0.9 3,156,162 + +1.6 3,156,163 - -1.1 3,156,222 + -0.9 3,156,223 - -0.4 3,156,637 - Rv2848c 0.36 -2.4 3,156,941 + Rv2848c 0.58 -1.6 3,156,941 + Rv2848c 0.58 +0.9 3,156,942 - Rv2848c 0.58 +0.6 3,156,942 - Rv2848c 0.58 -0.3 3,156,942 - Rv2848c 0.58 -1.7 3,157,312 - Rv2848c 0.85 +1.9 3,157,402 + -0.1 3,157,721 - Rv2849c 0.32 -0.3 3,157,841 + Rv2849c 0.51 +0.3 3,157,842 - Rv2849c 0.51 +0.7 3,158,152 + -0.4 3,158,153 - -0.4 3,158,157 - -0.2
Or see this region's nucleotide sequence