Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2741

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ofloxacin 0.8 ug/mL
3,053,220	+				+1.4
3,053,221	-				-1.4
3,053,369	-		Rv2740	0.30	+0.8
3,053,599	+		Rv2740	0.81	+0.0
3,053,599	+		Rv2740	0.81	+0.3
3,053,600	-		Rv2740	0.82	-0.1
3,053,611	+		Rv2740	0.84	+0.5
3,053,611	+		Rv2740	0.84	+1.2
3,053,611	+		Rv2740	0.84	+0.5
3,053,612	-		Rv2740	0.84	+1.0
3,053,612	-		Rv2740	0.84	-0.4
3,053,714	+				-0.7
3,053,715	-				-0.5
3,053,715	-				+0.9
3,053,757	-				-1.2
3,053,763	-				+1.3
3,053,831	-				-1.3
3,053,832	+				+2.2
3,053,833	-				+0.2
3,053,833	-				+0.0
3,054,097	+		Rv2741	0.12	+0.1
3,054,097	+		Rv2741	0.12	+0.2
3,054,097	+		Rv2741	0.12	+0.8
3,054,098	-		Rv2741	0.12	+1.9
3,054,166	+		Rv2741	0.16	+0.5
3,054,172	+		Rv2741	0.16	+0.0
3,054,172	+		Rv2741	0.16	+0.8
3,054,173	-		Rv2741	0.16	+0.3
3,054,173	-		Rv2741	0.16	+0.2
3,054,227	+		Rv2741	0.20	+1.0
3,054,227	+		Rv2741	0.20	+0.1
3,054,228	-		Rv2741	0.20	+0.1
3,054,286	-		Rv2741	0.24	+0.9
3,055,022	+		Rv2741	0.70	-0.1
3,055,022	+		Rv2741	0.70	+1.9
3,055,023	-		Rv2741	0.70	+1.0
3,055,023	-		Rv2741	0.70	+0.6
3,055,023	-		Rv2741	0.70	+1.3
3,055,024	+		Rv2741	0.70	-1.3
3,055,024	+		Rv2741	0.70	+0.1
3,055,143	+		Rv2741	0.78	+0.8
3,055,148	+		Rv2741	0.78	+0.6
3,055,148	+		Rv2741	0.78	+2.2
3,055,148	+		Rv2741	0.78	+1.1
3,055,149	-		Rv2741	0.78	+0.8
3,055,149	-		Rv2741	0.78	-0.2
3,055,149	-		Rv2741	0.78	-0.0
3,055,149	-		Rv2741	0.78	+0.5
3,055,149	-		Rv2741	0.78	+0.8
3,055,192	+		Rv2741	0.81	-0.3
3,055,193	-		Rv2741	0.81	+0.6
3,055,320	-		Rv2741	0.89	+2.8
3,055,320	-		Rv2741	0.89	+2.9
3,055,336	-				+0.4
3,055,336	-				+0.3
3,055,486	-				+1.9
3,055,781	+		Rv2742c	0.32	-0.7
3,055,919	-		Rv2742c	0.48	+0.0
3,055,932	+		Rv2742c	0.50	+1.3
3,055,932	+		Rv2742c	0.50	-0.0
3,055,940	+		Rv2742c	0.51	+1.0
3,055,941	-		Rv2742c	0.51	+0.9
3,055,941	-		Rv2742c	0.51	+0.5
3,056,006	+		Rv2742c	0.59	+2.2
3,056,061	+		Rv2742c	0.65	-0.0
3,056,061	+		Rv2742c	0.65	-1.2
3,056,061	+		Rv2742c	0.65	+0.6
3,056,061	+		Rv2742c	0.65	+1.3
3,056,062	-		Rv2742c	0.66	+0.6
3,056,062	-		Rv2742c	0.66	+1.1
3,056,062	-		Rv2742c	0.66	+0.4
3,056,070	+		Rv2742c	0.67	+0.3
3,056,077	-		Rv2742c	0.67	+1.2
3,056,266	-				+1.0
3,056,290	+				+0.3
3,056,291	-				+0.6
3,056,291	-				-0.2
3,056,382	+				+1.3
3,056,383	-				+0.3
3,056,383	-				+0.8
3,056,385	-				+0.9
3,056,385	-				-0.4