Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2402

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ofloxacin 0.8 ug/mL
2,697,651	+				-1.0
2,698,043	+				+1.0
2,698,248	+				+0.0
2,698,248	+				+1.0
2,698,249	-				+0.3
2,698,287	-				+0.4
2,698,287	-				+0.1
2,698,330	+				-0.3
2,698,331	-				+0.5
2,698,536	+				+0.4
2,698,840	+		Rv2402	0.16	-0.0
2,698,840	+		Rv2402	0.16	+0.3
2,698,983	-		Rv2402	0.24	+0.2
2,699,025	-		Rv2402	0.26	+0.2
2,699,038	-		Rv2402	0.26	+1.3
2,699,038	-		Rv2402	0.26	-0.1
2,699,038	-		Rv2402	0.26	-0.6
2,699,201	+		Rv2402	0.35	+0.5
2,699,295	-		Rv2402	0.40	-1.1
2,699,417	+		Rv2402	0.46	-0.7
2,699,418	-		Rv2402	0.46	-0.2
2,699,459	+		Rv2402	0.48	+0.5
2,699,459	+		Rv2402	0.48	+0.1
2,699,460	-		Rv2402	0.48	-0.4
2,699,558	+		Rv2402	0.53	+1.0
2,699,616	-		Rv2402	0.56	-0.1
2,699,654	+		Rv2402	0.58	-1.4
2,699,655	-		Rv2402	0.58	+1.1
2,699,655	-		Rv2402	0.58	-0.4
2,699,703	-		Rv2402	0.61	-0.0
2,699,742	+		Rv2402	0.63	-0.3
2,699,743	-		Rv2402	0.63	-1.1
2,699,743	-		Rv2402	0.63	+0.2
2,700,006	-		Rv2402	0.77	+0.5
2,700,140	+		Rv2402	0.84	-0.4
2,700,214	-		Rv2402	0.87	+2.0
2,700,455	+				-0.2
2,700,455	+				+0.3
2,700,709	+		Rv2403c	0.23	+0.4
2,701,439	-				+0.6