Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1958c

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ofloxacin 0.8 ug/mL
2,202,115	+				-0.9
2,202,115	+				-0.8
2,202,123	+				-0.7
2,202,314	+		Rv1956	0.39	+0.4
2,202,377	+		Rv1956	0.53	+0.3
2,202,377	+		Rv1956	0.53	-0.5
2,202,377	+		Rv1956	0.53	-0.7
2,202,390	+		Rv1956	0.56	+0.7
2,202,390	+		Rv1956	0.56	+0.0
2,202,455	+		Rv1956	0.70	+2.9
2,202,455	+		Rv1956	0.70	+0.1
2,202,456	-		Rv1956	0.71	+1.1
2,202,729	-		Rv1957	0.27	+2.6
2,202,729	-		Rv1957	0.27	+1.3
2,202,773	-		Rv1957	0.35	-0.9
2,203,065	+				-0.1
2,203,065	+				-0.8
2,203,065	+				+0.6
2,203,066	-				+2.0
2,203,178	-		Rv1958c	0.26	-1.7
2,203,178	-		Rv1958c	0.26	-1.5
2,203,438	-		Rv1958c	0.68	+0.8
2,203,529	-		Rv1958c	0.83	+1.1
2,203,546	+		Rv1958c	0.86	-0.7
2,203,546	+		Rv1958c	0.86	-0.9
2,203,546	+		Rv1958c	0.86	+0.3
2,203,546	+		Rv1958c	0.86	+0.7
2,203,547	-		Rv1958c	0.86	-0.8
2,203,547	-		Rv1958c	0.86	+0.1
2,203,547	-		Rv1958c	0.86	+1.0
2,203,547	-		Rv1958c	0.86	+1.4
2,203,877	+		Rv1959c	0.66	+4.3
2,203,877	+		Rv1959c	0.66	-2.8
2,203,877	+		Rv1959c	0.66	+0.7
2,203,878	-		Rv1959c	0.66	-0.4
2,203,910	+		Rv1959c	0.77	+0.4
2,203,910	+		Rv1959c	0.77	-1.4
2,203,911	-		Rv1959c	0.77	+1.1
2,203,911	-		Rv1959c	0.77	+0.1
2,203,964	+				-0.7
2,203,964	+				-0.1
2,204,003	+		Rv1960c	0.12	+0.0
2,204,003	+		Rv1960c	0.12	-0.3
2,204,188	+		Rv1960c	0.85	-1.7
2,204,188	+		Rv1960c	0.85	-0.1
2,204,219	+				+1.1
2,204,249	+				-0.9
2,204,259	+				-0.1
2,204,389	+		Rv1961	0.36	-0.1
2,204,390	-		Rv1961	0.36	-0.0
2,204,401	+		Rv1961	0.38	-0.8
2,204,402	-		Rv1961	0.38	+0.5
2,204,402	-		Rv1961	0.38	-0.9
2,204,402	-		Rv1961	0.38	-0.1